Cutaneous Photosensitivity Flashcards
What is cutaneous photosensitivity
An abnormal skin ( cutaneous) response to UV reaction and sometimes visible light
2 types
What are the 2 types of cutaneous photosensitivity
Phototoxicity : skin and eyes are v sensitive to light
Photoallergy - form of allergic contact dermititis
What is the classification called that is used
Fitzpatrick sun reaction skin photo types
What is skin type 1
Always burns, never tans
Type II
Burns easily, poorly tans
Type III
Tans after initial burns
Type IV
Burns minimally, tans easily
Type v
Rarely burns, tans darkly easily
Type VI
Never burns, always tans darkly
What is porphyrins
Essentials for your haem - too much can cause issues :(
What are the 3 conditions associated porphyrins
Porphyria cutanea tarda
Erythropoietic protoporphyria
Acute intermittent porphyria
What enzyme is reduced in porphyria cutanea tarda.. its a hepatic problem
Uroprophyrinogen decarboxylase
Presentation of porphyria cutanea tarda
Blisters, fragility Hyperpigmentation Hypertrichosis Solar urticaria Morpholea
Ix of porphyria cutanea tarda
Wood light
Management of porphyria cutanea tarda
Relieve skin disease
Treat underlying cause e.g. alcohol, viral hep, oestrogen, haemochromatosis