Cutaneous Photosensitivity Flashcards

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1
Q

What is cutaneous photosensitivity

A

An abnormal skin ( cutaneous) response to UV reaction and sometimes visible light
2 types

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2
Q

What are the 2 types of cutaneous photosensitivity

A

Phototoxicity : skin and eyes are v sensitive to light

Photoallergy - form of allergic contact dermititis

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3
Q

What is the classification called that is used

A

Fitzpatrick sun reaction skin photo types

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4
Q

What is skin type 1

A

Always burns, never tans

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5
Q

Type II

A

Burns easily, poorly tans

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6
Q

Type III

A

Tans after initial burns

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7
Q

Type IV

A

Burns minimally, tans easily

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8
Q

Type v

A

Rarely burns, tans darkly easily

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9
Q

Type VI

A

Never burns, always tans darkly

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10
Q

What is porphyrins

A

Essentials for your haem - too much can cause issues :(

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11
Q

What are the 3 conditions associated porphyrins

A

Porphyria cutanea tarda
Erythropoietic protoporphyria
Acute intermittent porphyria

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12
Q

What enzyme is reduced in porphyria cutanea tarda.. its a hepatic problem

A

Uroprophyrinogen decarboxylase

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13
Q

Presentation of porphyria cutanea tarda

A
Blisters, fragility 
Hyperpigmentation 
Hypertrichosis 
Solar urticaria 
Morpholea
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14
Q

Ix of porphyria cutanea tarda

A

Wood light

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15
Q

Management of porphyria cutanea tarda

A

Relieve skin disease

Treat underlying cause e.g. alcohol, viral hep, oestrogen, haemochromatosis

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16
Q

Enzyme reduced in erythropoietic protoporphyria

A

Ferrochelatase

17
Q

Presentation of erythropoietic protoporphyria

A

Nothing is visible, all symptoms

18
Q

Ix of erythropoietic protoporphyria

A

Quantitative RBC porphyrins
Genetic testing
Transaminases

19
Q

Management of erythropoietic protoporphyria

A

Education really e.g. avoid middle of the day

20
Q

What enzyme is reduced in acute intermittent porphyria

A

Porphobilogen deaminise

21
Q

Presentation acute intermittent porphyria

A

Doesnt really affect skin

22
Q

Which one only affects children

A

Erythropoietic protoporphyria