Bacterial Virulence Flashcards
What is virulence
That things that virus acquire to make themselves better
What is adhesion
Enables binding of the organism to host tissue
What is invasion
Enables the organism to invade a host cell /tissue
What is impedin
Enables the organisms to avoid host defence mechanism
What is aggression
Causes damage to the host directly
What is modulin
Induces damage to the host indirectly
Where is staph aureus found on the skin
Where you put COVID swabs and perineum
What can s.aureus cause
Superficial lesions: boils -> abscess
Systemic : life threatening.. toxic shock and scalded skin syndrome
What virulence factors do s.aureus have
Fibrinogen binding protein ( adhesion) Haemolysin alpha ( cytolytic) Coagulase ( clots plasma) Leukocidin ( inactivated leukocytes) Protein A ( antiphagocytic) TSST - 1 - caused toxic shock, rash, desquamation
What is the diagnosis criteria of toxic shock syndrome
Fever ( 39)
Diffuse macular rash and desquamation ( sun burn)
Hypotension <90mmhg
>3 Organ system involved
Where is s. Epidermidis found
Mucous membranes
What is the most common cause of bacterial pharyngitis
Step pyogenes
What do step pyogenes cause
Impetigo
Cellulitis
Necrotising fasciitis
What is necrotising facitiis
Bacterial infection spreading along fascial planes below skin surface, rapid tissue destruction
Wont see any thing on skin but severe PAIN
Urgent surgical debridement
