CT Tissue Disorders And Systemic Disease To The Skin

Question 1

Inflammatory myopathy of voluntary muscles with associated skin rash

Answer 1

Dermatomyositis

Question 2

Systemic sclerosis

Answer 2

Rare, multi - system
Characterised by fibrosis of the skin and visceral organs and accompained by the presence of specific antinuclear antibodies

Question 3

Erythema nodosum
Scar sarcoidosis
Lupus pernio
Scarring alopecia

Answer 3

Sarcoidosis

Question 4

Most common porphyria

Sun exposed areas

Answer 4

Porphyria cutanea tarda

Question 5

Painful
Ulcerating disease of unknown cause
Typically affects the legs

Answer 5

Pyoderma gangrenosum

Question 6

Autosomal dominant inherited disorder due to the mutation in the neurofibromin gene
Characterised by cafe au lait and neurofibromas

Answer 6

Neurofibromatosis type 1

Question 7

Itchy, blistering condition also with coeliac disease

Answer 7

Dermatitis herpetiformis

Question 8

Facial telangiectaisa 
Restricted mouth opening 
Periorla puckering 
Smooth, shiny and pigmented skin 
Sclerodactyly 
Livedo reticularis 
Leg ulcers

Answer 8

Systemic sclerosis

Question 9

Heliotrope rash around the eyes

Gottrons papules

Answer 9

Dermatomyositis

Question 10

Discoid lupus erythematous
Malar rash 
Photosensitivity 
Vasculitis 
Raynaud’s phenomenon 
Alopecia

Answer 10

Lupus erythematosus

Question 11

Management for dermatomyositis

Answer 11

Oral steroids

Question 12

Management for pyoderma gangrenosum

Answer 12

Topical steroids / calcineurin inhibitors

If severe: systemic immunosuppressive treatment

Question 13

Antibodies against hemidesmosomes

Answer 13

Bullous pemphigoid

Question 14

Malar rash, poly arthritis, pleuritis, miscarriage

Answer 14

SLE

Question 15

Anti- dsDNA

Answer 15

SLE

Question 16

Anti - centromere

Answer 16

Limited cutaneous slceroderma

Question 17

Anti - Ro

Answer 17

Sjögren’s syndrome

Question 18

Anti - jo

Answer 18

Polymyositis or dermatomyositis