Crash Course in Immunology pt.1 Flashcards
Innate Immunity
Born with
always present
provides initial protection
nonspecific, general, fast response
Adaptive Immunity
Develops more slowly
Meditates later defense
Stimulated by specific pathogen
More effective
Chemical factors in innate immunity as a first line of defense
Lysozyme: tears, saliva, nasal secretion
- Digest peptidoglycan of bacteria
Gastic Juice: low pH destroys microbes and toxins
Physical factors in innate immunity as a first line of defense
Skin
Mucous Membranes
Mucos
Cilis
Roles of defensive cells in innate immunity as a second line of defense
Defensive Cells:
Phagocytes
Natural Killer cells
signs and symptoms of inflammation
Sign: heat, swelling, redness
Symptom: pain
Purpose of Inflammation
Response to cell damage
Confines and destroys microbes, initiates tissue repair
Basic stages of Inflammation
1.) tissue damage
2.) vasodilation, increased blood vessel permeability and blood clotting
3.) Phagocyte migration and phagocytosis
4.) Tissue repair
Role of fever
inhibits growth of microbes
speeds up repair reactions
Disadvantages: tachycardia, dehydration, seizures, death (112-144)
Role of complement system
group of serum proteins
complement immune response
Role on Interferons
antivirals secreted by infected calls
tell uninfected cells to protect themselves
Skin
forms physical barrier to entrance of micobes
Mucous Membranes
inhibit entrance of microbes
Mucos
traps microbes
Cilis
propel microbes upward out of lungs
