Contraception And Family Planning Flashcards
Wha are the mechanisms of action for contraceptions?
-Inhibiting the development and release of the egg
-Imposing a mechanical, chemical, or temporal barrier between sperm and egg
What is the def of secondary mechanism for contraception?
Alter the ability of the fertilized egg to implant and grow
*emergency
Can antibiotics decrease the efficacy of contraception?
NO
What is the pearl index?
The measure of unintended pregnancies from 100 women during 1 year of contraceptive use
*lower the score the lower the amount of unintended pregnancy
What is the def of typical (actual) failure rate
Failure rate seen with the method when it is actually used by the patients
*takes into account mistakes or noncompliance
What is the def of method failure rate?
Patient is using the method perfectly
*but the method is failing
When taking estrogen what does that increase the risk of?
Blood clots
What is the purpose of contraceptions?
They inhibit ovulation
When will the lining of the uterus shed?
When progesterone levels drop
When does ovulation occur?
When luteinizing hormone is at its peak
*LH recruits a follicle
What are combination pills made with?
Estrogen ad progestin
What is in the estrogen component of a combination pill
Ethinyl estradiol or newer estradiol valerate
What is in the progestin component of a combination pill
One of the 19-nortestosterone or spironolactone derivative
What is the MOA of a combination pill?
Suppresses the pituitary production of FSH and LH
What is the MOA of progesterone?
-Provides the major contraceptive effect
-suppresses secretion of LH and in turn ovulation
*thickens cervical mucus
What is the MOA of Estrogen?
Suppresses secretion of FSH
Prevents maturation of a follicle
What is breakthrough bleeding?
Spotting
*Bleeding that occurs outside the normal menstrual cycle
What is antithrombin III (ATIII)
-A potent inhibitor of the coagulation cascade
*can cause clotting
What are the effects of progestin/
Increase sebum
Stimulate the growth of facial hair and body hair
Induce smooth muscle relaxation
What are the “Phasic” regimens of (OCP)
Monophasic
*same dose in each pill each day
*21 days, 7 days placebo
Biphasic
*Same amount of estrogen each day
*Progestin dose is increased halfway
Triphasic
*three varying doses of hormones
What are continuous regimens of OCP?
Extends the cycle to every 3 months
*shorter and less frequent menses
What is the 365 day pill?
Amethyst
*28 active pills
*no placebo pills
*no menstrual cycle for the year
What is the progestin only pill?
Mini-pill
*camila, Errin, jolivette, Heather, and micronor
*Makes cervical mucus thick
When should progestin only pills be used?
Lactating women
*If not exclusively breastfeeding may become pregnant while on the pill
Women over age 40
What group of women are contraindicated to estrogen?
At risk CVD
Smokers
What are some disadvantages of POP
-Must be taken at the same time each day
*>3 hours late when taking the pill, the backup method should be used
What are some OCP advantages
Reduces the risk of iron-deficiency anemia
Lower incidence of endometrial and ovarian cancer
What are OCP disadvantages
Venous thrombosis
*clotting
Hepatic tumors
Cholestasis and gallbladder disease
When does breakthrough bleeding occur?
MC reason when discontinuing OCP
*MC during first 3 months of use
*counsel to expect irregularities
What is the only proven antibiotic that can reduce the efficacy of OCP
Rifampin
What is a first day start?
If you start bleeding take the pill
*provides the maximum contraceptive effect
What is a Sunday start?
Start first Sunday after menses onset
*use secondary form for first 7 days
What is a quick start?
Start on the day it is prescribed
*back-up form for 7 days
*confirm the patient is not pregnant
What are some contraindications of OCP?
Women over 35 years who smoke
Migraine
What does the transdermal patch contain?
Estrogen and progestin
How long is the patch effective for?
The entire week
*start patch during the first 5 days
*replace weekly for 3 weeks
*4th week is patch-free