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Immunology > Complement > Flashcards

Complement Flashcards

0
Q

Lectin pathway

A

lectins (mannose-binding lectin) bind to microbial surface polysacchardies

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1
Q

Alternative pathway

A

microbial cell walls, abnormal cells (virus-infected), foreign material (asbestos)

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2
Q

Classical pathways

A

IgG or IgM binding to microbial Ags

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3
Q

Complement Activation Pathways

A

alternative, lectin, classical

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4
Q

consequences of complement

A

inflammation
opsonization
microbial killing

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5
Q

inflammation due to complement

A

mast cell activation: C3a, C5a

leukocyte chemotaxis: C5a

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6
Q

opsonization due to complement

A

facilitates phagocytosis: C3b

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7
Q

microbial killing (Membrane Attack Complex) due to complement

A

forms pores in membranes: C5b

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Immunology (19 decks)

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