Coeliac Disease Flashcards
Malabsorption
causes
Coeliac Chronic pancreatitis Liver cirrhosis Biliary obstruction Crohn’s
Malabsorption
Clinical features
Diarrhoea Steatorrhoea Abdo distention Flatulence Deficiencies Weight loss
Aetiology
Autoimmune disorder
Genetic
Environmental
Immunological
Symptoms
Variety Lethargy Depression Vomiting Anaemia
Children - delayed puberty, behaviour changes, learning difficulties
Diagnosis
Broad symptom range makes difficult
Often misdiagnosed
IgA test (some IgA deficient) Biopsy (gold standard)
Classification
Classical Atypical Silent Latent Refractory
At risk
Family history
T1DM
Primary biliary cirrhosis
Autoimmune liver disease
Other associated conditions
Osteoporosis Anaemia IBS Infertility Neurological disorders Malignancy
Oats
50-70g/d
Pure uncontaminated may be include for majority
adds iron, soluble fibre, thiamine + zinc to diet
Codex-wheat starch
Manufactured wheat where gluten has been removed
Improved quality + texture therefore adherence
Other dietary considerations
Malt extract Secondary lactose intolerance Alcohol Anaemia Fibre Ca
Non-adherence reasons
Absence of symptoms Eating out/holiday Inadvertent consumption Social reasons Lack knowledge
Treatment
GF diet for life
Dietetic consultation
Est current understanding GF diet for treatment + reduce long-term complications Feedback on current diet GF prescription Samples from manufacturer Tests to identify possible deficiencies (@ diagnosis) Coeliac UK membership Calcium Iron + fibre
Dermatitis Hepetiformis
Dermatological manifestation of CD
~60% have no gut symptoms
Affects fewer people than coeliac disease
Treatment - GF diet, dapsone
