CNS - dementia, epilepsy, brain infections, parkinsons, tumours Flashcards

1
Q

Detecting Dementia

A

TSH - enurse thyroid function

CT scan

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2
Q

Alzheimers Disease

A

Leads to defects of

  • visual
  • spatial skill (gets lost)
  • memory loss
  • decreasing cognition
  • ansognosia (lack of awarness)
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3
Q

‘plaque and tangle’

A

terms of alzheimers disease under microscope

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4
Q

Treatment for Alzheimers Disease

A
  • MDT approach
  • Cholinelerase inhibitors - slow down progression
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5
Q

What is Epilespy?

A

A recurrent tendency to spontaneous intermittent abnormal electical activity in part of the brain, manifest as seizures

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6
Q

Types of seizures

A
  • focal twitching
  • tranc-like (absent)
  • convulsion
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7
Q

Causes of seizures

A
  • No identified cause
  • strokes
  • alcohol withdrawal
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8
Q

Diagnosis of seizures

A
  • Good history taking
  • Exlcude structural abnormality
  • EEG
  • Any possible triggers? lights, tv
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9
Q

Managment of seizures

A
  • depends on seizure type
  • drugs have serious side effects - need monitoring reg
  • drugs dangerous during pregnancy
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10
Q

Infections on the brain

A
  1. Diffuse infection - eg meningitis
  2. Focal infection - eg abcess
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11
Q

Meningitis - infection on the brain

A
  1. Bacterial - neisseria meningitidis and pneumococcus
  2. Viral - less severe
  3. Fungal - rare
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12
Q

Presentations of Meningitis

A

Early:

Headache, colds hands and feet, pyrexial (raised temp)

Late:

Necky stiffness, photophobia, Kernigs signs, non-blaching rash, seizures

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13
Q

Brain Abscess

A
  • focal infection
  • focal brain daage or mass effect
  • presents with headaches, seizures, temp
  • ‘ring enhancing lesion
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14
Q

Brain abcess can spread via

A

Blood:

  • Embolus from bacterial endocarditis
  • IV drug users

Direct:

  • from infected inner ear
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15
Q

Parkinson’s disease

A

Occurs in the Substantia nigra

  • Rigidity
  • Bradykinesis
  • Resting tremor
  • Postural instability

Treamtent:

  • MDT approach
  • Anticholinergc drugs
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16
Q

Tumours in the Brain/ Occuyping lesions

A
  • Benign or malignant
  • Benign depending on how big th tumour is, locaton and mass effect
  • can effect the skull, the meninges or the brain itself
17
Q

Presentation of tumours

A
  • Headache
  • Seizures
  • Cognitive or behavioural change
  • Vomiting
  • Altered conciousness
18
Q

Metastasis tumours

A

Cancer elsewer in the body can metastaize in the brain

  • Small cell lung cancer
  • Breast
19
Q

Meningioma - (benign tumour)

A
  • Benign tumour
  • Slow growing
  • Dont often infilerate the brain, can be removed surgically
  • Can be found on brain imaging scans
  • Derived from meningothelial cells
20
Q

Astrocytoma - tumour

A

Type of cancer in the brain
Graded 1 to 4 - 4 being fatal

Glioblastoma - has ring around it

21
Q

Pituitary Tumours

A
  • Can cause compression symptoms
  • Horomonally active
  • -Surgically removed transphernoidally