CMB1004/L28 Adrenal Glands Flashcards
Describe the location of the adrenal glands anatomically.
Sit on top of each kidney
What is the combined weight of adrenal glands in an adult?
8-10g
What kind of hormones are produced in the cortex of the adrenal glands?
Steroid hormones
What kind of hormones are produced in the medulla of the adrenal glands?
Amino acid hormones
What kind of tissue is the adrenal cortex derived from?
Mesodermal tissue surrounding kidneys
What kind of tissue is the adrenal medulla derived from?
Neural crest tissues
What is the neurotransmitter of the sympathetic nervous system?
Norepinephrine
Give the 3 ‘zones’ of the adrenal cortex, from inside-outwards.
Zona reticularis
Zona fasiculata
Zona glomerulosa
What hormone is produced by the zona glomerulosa (outer layer)?
Aldosterone
What hormone acts on receptors in zona glomerulosa?
Angiotensin II
What hormones are produced by the zona fasiculata (middle layer)?
Cortisol and androgens
What hormones are produced by the zona reticularis (inner layer)?
Cortisol and androgens
What hormones are produced by the adrenal medulla?
Mostly epinephrine
Some pre-methylated noradrenaline
What enzyme is lacked in the zona glomerulosa?
17 alpha-hydroxylase
What kind of molecule is aldosterone?
Mineralocorticoid