Circulatory System Flashcards
The blood serves several important functions. What are they?
- carries substances to cells (O2, nutrients, hormones)
- carries substances away from cells (CO2, wastes)
- regulates the acid-base balance in the body through the use of buffers
- regulates body temperature by absorbing heat internally and releasing it peripherally (i.e., in the skin)
- helps defend against disease (WBCs, antibodies)
What are the three basic layers of the blood cells?
- tunica externa – connective tissue
- tunica media – smooth muscle & elastic connective tissue
- tunica interna – epithelial tissue
What kind of cells is the tunica media made of?
- smooth muscle
- elastic connective tissue
What is the elastic connective tissue of the tunica media. important?
- allows the blood vessel to stretch and recoil as the pressure within it fluctuates
What is the smooth muscle of the tunica media important?
- regulates the diameter of the blood vessel (primarily controlled by the ANS)
What is the lumen?
- is the inside space of a tubular structure, such as an artery
What are the five types of blood vessels?
- arteries
- arterioles
- capillaries
- venules
- veins
Describe the purpose and structure of arteries.
- carry blood away from the heart
- have relatively thick walls which allows for an increased ability to stretch with each heartbeat
What are elastic arteries?
- largest arteries
- consists of the aorta and the major branches
- tunica media is predominantly elastic connective tissue
Why are the elastic fibres in elastic arteries important?
- recoil of these elastic fibres helps propel blood away from the heart
What are muscular arteries?
- medium-sized arteries
- tunica media is predominantly smooth muscle
Why is smooth muscle important in muscular arteries?
- abundance of smooth muscle allows for more control of blood flow
What are arterioles?
- “little arteries”
- small blood vessels that connect arteries to capillaries
What type of cells are the tunica media in arterioles made up of and why?
- contains lots of smooth muscle, which is used to tightly regulate the
amount of blood entering capillaries
What are capillaries?
- very small, highly-branched blood vessels that form networks among the individual cells of the body
- do not contain a tunica externa or tunica media
Why are the walls of capillaries so thin?
- allow the exchange of substances between the blood and surrounding cells
What are venules?
- “little veins”
- small blood vessels emerging from capillaries that start the route back to the heart
What do veins do?
- carry blood to the heart
- have relatively thin walls
- would essentially collapse if they were not filled with blood
What mechanisms assists the flow of blood through the veins?
- pumping action of the heart
- valves that prevent the back flow of blood
- “skeletal muscle pump”
- “respiratory pump”
What is skeletal muscle pump?
- contraction of skeletal muscles compresses the veins of the upper and lower limbs
What is respiratory pump?
- fluctuations in abdominal cavity pressure during respiration compresses abdominal veins
What is deep vein thrombosis (DVT)?
- clot (thrombus) may form in a deep vein (most common in the lower limbs)
What are the risk factors of deep vein thrombosis?
- trauma, long periods of immobilization (e.g., flights, casts), certain drugs (e.g., HRT, oral contraceptives)
What are some symptoms of DVT (if present)?
- swelling/warmth, local pain/tenderness, distension of superficial veins
What is a pulmonary embolism (PE)?
- a clot can detach (embolus) and get trapped within blood vessels
What are some symptoms of PE?
- chest pain, shortness of breath, cyanosis (bluish cast to the skin and mucous membranes)
- can affect both sides of the heart, which can lead to cardiac arrest and death
Are there more veins or arteries?
- veins greatly outnumber arteries
What is systolic blood pressure?
- pressure on arterial walls during ventricular contraction
What is diastolic blood pressure?
- pressure on arterial walls during ventricular relaxation
What is “mmHg”?
- the pressure exerted by 1mm of mercury
What controls the feedback systems of cardiovascular regulation?
- controlled by the cardiovascular (CV) centre in the medulla oblongata
- receives input from various sources and relays output signals to the heart and blood vessels via the ANS
Where does the input to the cardiovascular center (brain) come from?
- from higher brain centers
- proprioceptors (joint movements)
- baroreceptors (blood pressure)
- chemoreceptors (blood acidity)
Where does the output from the cardiovascular center (brain) go?
- heart (decreased and decrease HR, contractility)
- blood vessels (vasoconstriction)
Which nerves aid in the output of the cardiovascular center (brain)
- vagus nerve (parasympathetic)
- cardiac accelerator nerves (sympathetic)
- vasomotor nerves (sympathetic)
What is systemic circulation?
- system of blood vessels that carry oxygenated blood from the heart to the majority of the body and return deoxygenated blood to the heart
- blood LOSES oxygen
What is pulmonary circulation?
- system of blood vessels that carry deoxygenated blood from the heart to the lungs and return oxygenated blood to the heart
- blood GAINS oxygen
What is the largest artery in the body?
- the aorta
What are the four sections of the arteries of systemic circulation?
- arch of the aorta (head, neck, upper limbs)
- thoracic aorta
- abdominal aorta
- ascending aorta (heart)