CIPROFLOXACIN Flashcards
TYPE OF ANTIBIOTIC?
Quinolone
can it be prescribed for mild infections?
no, only give in severe non self limiting infections
oral dose if renal impairment?
250-500mg every 12 hours if 30-60ml/min
every 24 hours if <30
IV dose adjustment?
200-400mg every 12 hours if 30-60ml/min
every 24 if <30
who shouldnt use this medication?
patients with seizures, diabetes, epilepsy history, psychiatic disorders
tendon disorders related to quinolone use, CS use, tendinitis
use in children
only if risks outweigh the benefits
can cause arthropathy in the weight bearing joints of immature animals
adverse events to monitor
acute myocardial infarction- QT prolongation is a risk factor
corneal deposits if drops
arthropathy in children
use in pregnancy? BF?
avoid and use safer options
single dose can be given for prevention of secondary case meningococcal meningitis
eye: only if risks outweigh the benefits
caution in BF
side effects?
prolong QT interval, arthropathy
aortic aneurysm and dissection
musculoskeletal and nervous system effects
patient counselling
cant go in the sun for 48 hours after
avoid use with dairy and mineral fortified drinks (reduces exposure)
may affect performance of skilled based tasks e.g. driving
increased risk of convulsions when taken with what
NSAIDS
TF: ciprofloxacin can only cause convulsions in patients with history of seizures
FALSE, anyone
when should it be discontinued
sudden onset severe abdo, chest or back pain- aortic aneurysm
tendinitis, muscle pains, joint pains, neuropathy- musculoskeletal and nervous system side effects
rapid onset SOB, especially when lying down flat, swelling of the ankles, feet or abdomen, new onset heart palpitations- heart valve regurgitation
neurological, psychiatric, tendon or hypersensitivity reactions
risk factors of heart valve regurgitation?
past or pre-exsisting heart valve disease, connective tissue disorders, hypertension, RA, infective endocarditis
