CEFTAZIDIME Flashcards
1
Q
what is ceftazidime? MOA
A
cephalosporin which attaches to penicillin binding proteins to interrupt cell wall synthesis- leads to lysis and death
2
Q
what should you do to the dose if impaired eGFR?
A
if CrCl <50ml/min then reduce dose
3
Q
directions for ceftazidime to be given intravenously (1) for infusion
A
1: for infunstion: intermittently or via drip in glucose 5% or 10% or NaCl 0.9%
dissolve 2g in 10ml infusion fluid
4
Q
how should it be used in renal or hepatic impairment
A
caution
5
Q
what adverse effects should you monitor?
A
AKI
thrombocytosis, AB associated colitis, encephalopathy and jaundice
6
Q
use in pregnancy? milk?
A
isnt known to be harmful, present in milk in low concentrations but can still use
