Cholangiocarcinoma Flashcards
def
cancers arising from biliary duct epithelium
what can cholangiocarcinomas be divided into
intrahepatic
extrahepatic
what can extrahepatic cholangiocarcinomas be divided into
perihilar (close to liver)
distal (far from liver)
what are klastins tumours
perihilar extrahepatic cholangiocarcinomas which involve the bifurcation of the ducts
what is the most common type of biliary tract cancer
adenocarcinomas
epi
middle-aged to elderly
what are risk factors for intrahepatic cholangiocarcinoma
ALD B/C (hepatitis) cirrhosis + CLD choledocholithiasis + cholecystolithiasis UC +PSC
what is choledocholithiasis
bile stones in the bile duct
what is cholecystolithiasis
bile stones in the gallbladder
what are risk factors for intra and extrahepatic cholangiocarcinoma
alcoholism
OCP
what classification is used for perihilar (extrahepatic) tumours
bismuth-corlette
risk factors
elderly UC, PSC, ascending cholangitis choledocholithiasis + cholecystolithiasis liver disease hep B + C
what are common features of cholangiocarcinoma
painless jaundice
weight loss
abdominal pain
what is required for diagnosing cholangiocarcinoma
pathological diagnosis
how are cholangiocarcinomas imaged
1st line: USS
followed by CT or MRI
