Chapter 8 Flashcards

Alterations in immunity and inflammation

1
Q

which of the following is not characteristic of hypersensitivity

a. specificity
b. immunologic mechanisms
c. inappropriate or injurious response
d. prior contact unnecessary to elicit a response

A

prior contact unnecessary to elicit a response

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2
Q

When the body produces antibodies against its own tissue, it is

a. hypersensitivity/autoimmunity
b. an immunologic reaction/cell mediated immunity
c. alloimmunity/hypersensitivity
d. hypersensitivity/cell mediated immunity

A

hypersensitivity/ autoimmunity

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3
Q

Damage in glomerularnephritis is due to the formation of antigen/antibody complexes mediated by

a. IgE
b. mast cells
c. the cell mediated immune system
d. the humoral immune system
e. lymphokines

A

the humoral immune system

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4
Q

Which of the following is an alloummune disorder

a. graft rejection
b. insulin dependent diabetes
c. myxedema
d. all of the above are correct
e. none of the above are correct

A

graft rejection

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5
Q

The most frequently observed selective antibody-dependent immunodeficiency is a deficit of

a. IgA
b. IgD
c. IgE
d. IgG
e. IgM

A

IgA

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6
Q

An infusion of plasma may be used to treat

a. SCID
b. Thymus deficiencies
c. hypogammaglobulinemia
d. enzymatic defects

A

hypogammaglobulinemia

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7
Q

Deficiencies in B cell immune responses are suspected when unusual or recurrent severe infections are caused by

a. fungi
b. yeast
c. encapsulated bacteria
d. viruses

A

encapsulated bacteria

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8
Q

C6, C7, C8, and C9

a. lyse bacteria
b. activate inflammation
c. attract phagocytes
d. opsonize microbes

A

lyse bacteria

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9
Q

Cellular immunity neutralizes

a. bacterial toxins
b. viruses
c. bacteria
d. intracellular viruses

A

intracellular viruses

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10
Q

Which is characteristic of hypersensitivity?

a. sensitization required
b. occur on initial antigenic exposure
c. intolerance to self antigens
d. reactions may be immediate or delayed

A

Sensitization required
Intolerance to self antigens
Reactions may be immediate or delayed

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11
Q

When the body produces antibodies against antigens of the same species, it is an

a. hypersensitivity
b. antibody reaction
c. cell mediated immunity
d. alloimmune disease
e. opsonization

A

alloimmune response

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12
Q

Graves disease (match condition with the immunologic mechanisms)

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

cytotoxic/tissue specific

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13
Q

Serum sickness match condition with the immunologic mechanisms)

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

Immune complex

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14
Q

Allergic Rhinitis match condition with the immunologic mechanisms)

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

IgE mediated

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15
Q

Systemic lupus erythematosus (match condition with the immunologic mechanisms)

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

Immune complex

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16
Q

Contact dermatitis (match condition with the immunologic mechanisms)

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

cell mediated

17
Q

Hemolytic anemia (match condition with the immunologic mechanisms)

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

cytotoxic/tissue specific

18
Q

Graft rejection

a. cytotoxic/tissue specific
b. Immune complex
c. IgE mediated
d. cell mediated

A

cell mediated

19
Q

Sequestered antigen (Match with circumstance)

a. Traumatized tissue releases antigens
b. integration of drug into plasma membrane of a cell
c. both autoimmunity & alloimmunity

A

Traumatized tissue releases antigens

20
Q

Neoantigen (Match with circumstance)

a. Traumatized tissue releases antigens
b. integration of drug into plasma membrane of a cell
c. both autoimmunity & alloimmunity

A

integration of drug into plasma membrane of a cell

21
Q

Maternal antibody destroys platelets in the fetus & neonate

a. Traumatized tissue releases antigens
b. integration of drug into plasma membrane of a cell
c. both autoimmunity & alloimmunity

A

both authoimmunity & alloimmunity

22
Q

Antibody binds with receptors for neural transmitters on muscle cells (Match with circumstance)

a. Traumatized tissue releases antigens
b. alloimmunity
c. autoimmunity

A

autoimmunity

23
Q

B cell receptor signaling defect (Match the class of primary immunodeficiency with its consequence)

a. incomplete T cell maturation, normal B and NK
b. little or no b cell maturation or antibody
c. secondary C3 deficiency

A

little or no b cell maturation or antibody

24
Q

SCID:TCR defect (Match the class of primary immunodeficiency with its consequence)

A

incomplete T cell maturation, normal B and NK

25
Q

Alternative complement pathway defect cells

A

secondary C3 deficiency