Chapter 7 Flashcards
Adaptive Immunity
Immunogenicity depends on
a. Host foreignness
b. tolerance
c. chemical simplicity
d. low molecular weight molecules
Host foreignness
Which of the following are capable of forming clones
a. helper t cells
b. cytotoxic t cells
c. b cells
d. both T & B cells
Both T and B Cells
Which cells are stimulated by IL-2
a. b cells
b. t cells & NK cells
c. mast cells
d. thymic epithelial cells
T and NK cells
Which binds MHC class I molecules
a. helper t cells
b. cytotoxic t cells
c. b cells
d. both b & t cells
cytotoxic T cells
HLAs
a. when dissimilar in transplanted tissue or organs the more likely the transplant will be successful
b. are not found on the surfaces of erythrocytes
c. are found on the surfaces of very few human cells
d. are not MHC molecules
are not found on the surfaces of erythrocytes
CD4 markers are associated with
a. cytotoxic t cells
b. suppressor t cells
c. helper t cells
d. antigen presenting cells (APCs)
Helper T cells
Antibodies are produced by
a. b cells
b. t cells
c. helper t cells
d. plasma cells
e. memory cells
plasma cells
An immunoglobulin contains
a. two heavy and two light polypeptide chains
b. four heavy and four light polypeptide chains
c. two heavy and four light polypeptide chains
d. four heavy and two light polypeptide chains
two heavy and two light polypeptide chains
The antibody class that has the highest concentration in the blood is
a. IgA
b. IgD
c. IgE
d. IgG
e. IgM
IgG
Which of the following antibodies is matched with its appropriate role?
a. IgA/allergic reactions
b. IgD/found in respiratory secretions
c. IgE/found in gastric secretions
d. IgM/first to challenge the antigen
IgM,/first to challenge the antigen
The primary immune response involves
a. a rapid plasma cell response with peak antibody level by 3 days
b. macrophage production of antibodies
c. T cell production of antibodies
d. a latent period followed by peak antibody production
a latent period followed by peak antibody production
The B cell receptor (BCR) complex consist of:
a. IgG or IgD antibody
b. IgE or IgD antibody
c. antibody like transmembrane protein
d. antigen recognition molecules
antigen-recognition molecules
Cytokines and their receptors function
a. as intracellular chemical signals
b. as chemical signals between cells
c. as negative regulators of acquired immune responses
d. to decrease the production of proteins
as chemical signals between cells
Clonal selection
a. occurs primarily in the fetus
b. induces central tolerance
c. occurs primarily after birth and throughout life
d. occurs in central lymphoid organs.
c occurs primarily after birth and throughout life
Immunologic tolerance develops because
a. self reactive lymphocytes are eliminated in the primary lymphoid organs
b. self reactive lymphocytes are inactivated in the secondary lymphoid organs
c. lymphocytes remember their first exposure to the antigen
d. t cells may reprogram themselves by receptor editing
a self reactive lymphocytes are eliminated in the primary lymphoid organs
Endogenous antigens:
a. are carried on microorganisms that are phagocytized
b. are presented by class II major histocompatibility
c. may be produced by cancerous cells
d. are digested in lysosomal environment
c. may be produced by cancerous cells
Cytotoxic T cells:
a. inhibit extracellular viruses
b. inhibit virus infected cells
c. inhibit viral protein synthesis
d. decrease expression of MHC molecules
inhibit virus infected cells
Antibody is effective against
a. extracellular viruses
b. virus infected cells
c. viral protein synthesis
d. expression of MHC molecules
extracellular viruses
Transforming growth factor (TGF) functions to
a. increase phagocytosis
b. increase expression of MHC class II
c. Be chemotactic for neutrophils and T cells
d. stimulate wound healing
d) stimulate wound healing
______ are necessary to induce both humoral and cellular immune responses
a. Helper T cells
b amamnestic
c. regulatory T cells
helper T cells
A second challenge by the same, earlier antigen results in an __________ immune response characterized by more antibody production in a shorter time than the initial or first challenge
a. Helper T cells
b amamnestic
c. regulatory T cells
anamnestic
______ function to avoid attacking self antigens or avoid over activation of immune responses.
a. Helper T cells
b amamnestic
c. regulatory T cells
regulatory T cells
______ cause activation of large populations of T lymphocytes irrespective of antigen specificity.
a. Helper T cells
b superantigens
c. secretory immune system
Superantigens
The ______ consist of antibodies in bodily secretions, that protect the body against antigens yet to penetrate the skin or mucous membranes
a. Helper T cells
b superantigens
c. secretory immune system
secretory immune system
