chapter 5

Question 1

T/F: HTN is a multifactoral disease

Answer 1

True

Question 2

T/F: Fat intake is controlled by leptin and its receptors for genes

Answer 2

true

Question 3

T/F: A multifactorial trait is expressed when multiple genes and environmental influences blend together

Answer 3

true

Question 4

T/F: In down syndrome the pathology is manifested independent of environment

Answer 4

true

Question 5

T/F: It is easy to distinguish between the effects of shared environmental factors and the effects of a common pool of genes

Answer 5

false

Question 6

Psychiatric disorders depend on genes encoding for inhibitor neurotransmitters

Answer 6

false

Question 7

relative risk is a ratio between incidence and individuals

Answer 7

true

Question 8

early type 2 diabetes may develop when an individuals diet changes to include heavy carbohydrate consumption

Answer 8

true

Question 9

finding and understanding environmental factors that affect the penetrance of specific genes are important if chronic familial diseases are to be prevented

Answer 9

true

Question 10

a variation in the phenotype for different genotypes caused by environmental factors is a threshold liability trait

Answer 10

false

Question 11

the frequency of genetic disease in the population depends on phenotypes

Answer 11

false

Question 12

risk factors when removed or eliminated delay or prevent disease

Answer 12

true

Question 13

a proband is the individual who began the pedigree

Answer 13

true

Question 14

the recurrence risk is less when more than one sibling is affected

Answer 14

false

Question 15

the existence of a particular risk factor indicates that an individual will develop a specific disease

Answer 15

false

Question 16

the expression of a disease may require both an inherited defect and environmental exposure

Answer 16

true

Question 17

multifactorial diseases can change substantially from one population to another because gene frequencies and environments differ

Answer 17

true

Question 18

dizygotic twins are identical

Answer 18

false

di: indicates two eggs

Question 19

recurrence risk is higher if the disease is more severe in the proband

Answer 19

true

Question 20

the prevalence rate is the number of individuals affected with a disease

Answer 20

true

Question 21

the incidence rate is the number of people who have died from a disease

Answer 21

false

Question 22

Type 1 diabetes (match with environmental factors)

Answer 22

viral infections

Question 23

HTN (match with environmental factors)

Answer 23

minimal exercise

Question 24

Colon Cancer (match with environmental factors)

Answer 24

high fat, low fiber

Question 25

Coronary artery disease (match with environmental factors)

Answer 25

minimal exercise, elevated serum cholesterol