Chapter 7: Proteins and Amino Acids (Oct 18 Lec) Flashcards
Absorbed amino acids are used by the ____ (usually as fuel)
enterocyte
describe what happens to absorbed amino acids
they enter the portal blood supply, taken to live for metabolism
- used in current form to synthesize proteins:
- albumin (the major plasma protein)
- clotting factors
- acute phase proteins (inflammatory response)
- many other proteins
deamination and/or transamination
- synthesize non-essential AA
- convert C skeleton to glucose, lipids, or energy
Removal of ammonia from body
do animals have protein requirements?
no!
need amino acids
What “protein requirements” do monogastrics have?
the necessary indispensable AA, in the proper amount
AND
amino N (usually in the form of protein) to synthesize dispensable AA
What “protein requirements” do ruminants have?
- can rely entirely on microbial protein synthesis
- high producing animals need preformed dietary AA as well as microbial protein
T/F
microbes in ruminants can synthesize all 20 amino acids
true!
when is amino acid requirement highest?
at birth (declines with age) - related to growth rate (higher for growth than for maintenance)
T/F
amino acid requirement is always higher for males in all livestock species
False
not always- but usually
- sometimes will be higher for females (eg producing milk).
- usually higher for males b/c of larger body size, faster growth rate
Liebig’s Law of the Minimum
” a crop’s yield is restricted by the lack of a single element, even though there may be sufficient quantities of all other essential nutrients”.
Can be extended to animals and their resources (eg a single trace mineral can be the limiting factor)
protein synthesis cannot occur beyond the level of the ____ ____ ___
limiting amino acid
if protein synthesis is limited b/c of a deficiency of one amino acid, what happens?
other amino acids are broken down
Amino acid imbalance=
the dietary proportions of indispensable AA do not meet the needs of the animal (1 or more AA are limiting)
give an example of amino acid antagonism
Lysine and arg because they share a transporter
eg. if lysine is in excess, supplement arginine
T/F
toxicity of an AA can be overcome but supplementing another amino acid
false