Chapter 7: Mood Disorders -Textbook extras Flashcards
Ahedonia??
-inability to experience pleasure
What symptoms are central to a major depressive episode?
- physical symptoms
L> somatic/vegetative symptoms
In terms a manic episode what is the term flight of ideas referring to?
- rapid speech, incoherent because the individual is attempting to express many exciting ideas all at once
What is a dysphoric episode?
- when someone experiences manic symptoms but still feels somewhat depressed or anxious at the same time.
Major depressive disorder, single episode?
- absence of manic or hypomanic episodes before or during the episode
Major depressive disorder, recurrent?
- stats as well
- two or more major depressive episodes occurred and were separated by at least two months during which the individual was not depressed
85% experience another episode
After the death of someone the frequency of severe depression that follows is a high as __%. They however do/do not consider this a disorder ?
- 62%
- do not unless the symptoms are very severe like psychotic features or suicide ideation or the less alarming symptoms last longer than 2 months.
Natural grief normally lasts how long?
- several months up to a year, sometimes longer
After experiencing a year of grief what is the __% of those that do not recover due to absence of treatment and it turning into a disorder?
- 10-20% it becomes a disorder
When normal grief progresses to a disorder what is it called?
- pathological grief reaction or impacted grief reaction
L> intrusive memories and distressingly strong yearnings for the loved one, and avoiding people or places that are reminders of the loved one.
Bipolar II Disorder?
- major depressive episodes alternate with hypomanic episodes rather than full ones
Bipolar I Disorder?
- major depressive episodes alternate with full manic episodes
During manic episodes what do patients often do?
- they deny anything is wrong with them
Cyclothymic disorder??
- chronic alteration of mood elevation and depression that does not reach the severity of manic or major depressive episodes. They tend to exp one mood state for long periods of time (years) without very few periods of neutral/euthymic mood. (must lasts for two years)
Bipolar I and Bipolar II ages of onset?
onset proceeds what?
- stats of those that progress to BiD I
- is it common for someone to develop BiD after age 40?
- 18
- 22
- onset usually follows minor oscillations in mood or mild cyclothymic mood swings
- 13% with BiD II move on to BiD I
- rare
Suicide rates with BiD are?
12-48%
Postpartum onset specifier? applies to ?
characterized by?
stats for re-experiencing it?
- increases risk ?
- both Major depressive episodes and manic episodes
- severe manic or depressive episodes that first occur during the postpartum period ( four weeks) after child birth….two to three days after delivery..
- 50%
- infants with difficult temperaments, low socioeconomic status and high levels of life stress
What are the 3 specifiers for describing depression or mania?
- Longitudinal course specifiers
- Rapid Cycling specifiers
- seasonal pattern specifiers
- Longitudinal course specifiers? (4)
- history of mania or depression before?
- did they recover between episodes?
- did they have dysthymia before the episode - double depression
- cyclothymic disorder before?
- Rapid cycling specifier?
- stats who experience this
- who does this apply to
- suicide rates?
- do they being with a mania episode first just as people with BiD do in general?
- describe the cycles over time
- only to BiD II and I
- exp at least four manic or depressive episodes within a year is considered to have a rapid cycling pattern, does not respond well to treatments, higher chances of suicide
- 20% with BiD have this
- people with this begin with a depressive episode first rather than mania
- cycles without breaks, increasing in frequency
- Seasonal pattern specifier?
-includes?
-accompanies?
L> Disorder is called?
*explain it both for MDDR and BiD
- both BiD and recurrent major depressive disorder
- accompanies episodes that occur during certain seasons ex: winter depression
- Seasonal Affective disorder
L> Depression begins in fall, ends in spring
L> BiD: begins depression in winter and manic during the summer
What is weird with seasonal affective disorder and the depression experienced?
- Winter depression: excessive sleep instead of decreased sleep, increased appetite rather than decreased and weight gain rather than loss.
Biological explanation for SAD?
- Melatonin
- Circadian rhythms
- location?
- production of melatonin
L> increased production may trigger depression in vulnerable people
L> circadian rhythms are also thought to have some relationship with mood and are delayed in the winter - worse in extreme northern and southern latitudes because of the lack of sunlight
What mood disorder is very common in young children?
- dysthymia
Children below the age of __ seem to present with more ___ and __ swings rather than manic states and are often mistaken to as being __.
- 9
- irritability
- mood
- hyperactive
Children especially boys tend to become ___ and even ___ during depressive episodes.For this reason they are often misdiagnosed with ____ or even___. Often ____ and depression co-occur.
- aggressive, destructive
- conduct disorder or hyperactivity
- conduct disorder
Late onset depressions are associated with what symptoms?
- sleeping difficulties
- hypochondriasis
- complication of diagnosis because of other medical conditions in the elderly
What two disorders frequently accompany depression in elderly ? When depression accompanies one of these the depression is characterized as ?
- GAD and PD
- more severe depression
The gender imbalance with depression disappears after the age of?
65
Almost all depressed patients are anxious but ?
not all anxious patients are depressed
What are the core symptoms of depression that set it apart from anxiety?
- anhedonia
- cognitive content?
- slowing of ?
- anhedonia: inability to experience pleasure
- slowing of both motor and cognitive functions until they are extremely laboured and effortful
- cognitive content: (what is thought about) is usually really negative in depressed people vs anxious.
What are symptoms of negative effect in regards to depression and anxiety/panic?
- symptoms that are not specific to either of the disorders and help define each respectively
Major Depression usually follows ___ and may be a consequence of it.
anxiety
With depression there is also comorbidity with what personality disorder?
borderline personality disorder
self harm behaviour as well
Equifinality ?? Mood disorders?
- same end product (mood disorder) BUT multiple causes
Family studies suggest what about unipolar and bipolar disorders?
-mood disorders run in families
L> the proband (first degree relatives) with a mood disorder and their relatives have a high chance of acquiring it…. 2 to 3 times more so than the gen
Adoption studies and mood disorders?
- data is mixed
Twin studies and mood disorders?
- best evidence
- 66.7% twins (identical) 18.9% fraternal twins if one twin has bipolar
- 45.6% (identical) and 20.2 (fraternal) for if the first twin has unipolar
What plays a greater role in mood disorders, genetics or the environment for men and women?
- environment plays a larger role in causing depression in men than women.
Permissive hypothesis?
- when serotonin lvld are low, other NT are permitted to range more widely, become dysregulated, and contribute to mood irregularities including depression.
Dopamine agonist L-dopa seems to do what in bipolar patients?
- produce hypomania
HPA axis and depression?
- cortisol lvls are elevated in depressed patients ,