Chapter 6 BNF (Sex Hormone Responsive Conditions) Flashcards
Name some natural Oestrogens?
Estradiol
Estriol
Estrone
Name some synthetic Oestrogens?
Ethinylestradiol
Menstranol
What’s the treatment for vaginal atrophy?
Topical Oestrogens
What are the vasomotor symptoms Postmenopause ?
Hotflushes
Night sweats
What’s the treatment of vasomotor symptoms?
Systemic oestrogens
Patches
Clonidine
Where must oestrogen patches be applied?
Below waistline
Away from breast
Which HRT is recommendations for patients with no uterus?
Oestrogen only!
What type of combined HrT are available?
Cyclical or continuous
Which type of continuous HRT is recommended in peri menopausal women and women less than 12 months after last period ?
Cyclical
When should HRT be stopped before surgery?
4-6 weeks
Does HRT provide contraception?
No
What contraception is recommended in under 50 and over 50?
Under: combined (low oestrogen)
Over: barrier
What are side effects of HRT?
Ovarian
Breast
Cervical
Endometrial (add progestogen)
CHD: if started 10 years post menopause
What are some reasons to stop HrT?
VTE Stroke Liver BP (160/95) Cancer
What’s clomifene used for?
Ovulation stimulant
6 cycles