Chapter 2 BNF (Blood Pressure Conditions) Flashcards
First, Second and Third line in hypertension in Caucasian under 55?
First: ACE/ ARB or BB
Second: CCB, Thiazide
Third: ACE, CCB, Thiazide
First line in Hypertension in over 55 and Afrocaribbean?
First line: CCB or Thiazide
Second: ACE/ARB (ARB in afrocaribbean)
Third: ACE Thiazide + CCB
Thresholds for stages of hypertension?
1: 140/90
2: 160/100
3: 180/110 (hypertensive crisis)
Which patients should be treated in stage 1 hypertension?
Target organ damage (LV hypertrophy, CKD, retinopathy)
CVD or 10 year CVD risk of 20%
Renal disease
Diabetes
How is hypertensive crises treated in:
Acute organ damage
No organ damage
Organ damage: IV
Oral: over 24/48 hours
Over 80 target BP?
150/90
Under 80 target BP?
140/90
130/80 in atherosclerotic CVD or diabetes with kidney, eye, or cerebrovascular disease
Diabetes target BP?
140/80
130/80 with complications
Pregnant target BP?
150/100 in chronic hypertension
140/90 in organ damage or after birth
When should methyldopa be stopped after pregnancy?
2 days
Which ACE is taken twice daily?
Captoril
Which ACE should be taken 30-60 mins before food?
Perindopril
How do ace inhibitors affect the liver?
Cholestatic jaundice
Hepatic failure
Stop if liver transaminases 3x baseline or if jaundice occurs
Side effects of ACE?
Cough Oral ulcer Taste disturbance Hypoglycaemia Angioedema
Clonic one side effects?
Flushing