Chapter 4 BNF (Pain) Flashcards

1
Q

What’s best for MSK pain?

A

Non opioids

NSAIDs

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2
Q

What’s best for dental pain?

A

NSAIDs

Find cause

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3
Q

What can be offered for period pain?

A

Oral contraceptives
Antispasmodics
Non opioids

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4
Q

What can be offered for nerve compression by a tumour?

A

Dexamethasone

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5
Q

What dose aspirin should be given in medical emergencies?

A

Aspirin 300mg dispersinble or chewable. NOT Gastro resistant

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6
Q

What’s the aspirin dose for pain?

A

300-900mg every 4-6 hours

Max 4G

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7
Q

When can aspirin be used in under 16?

A

Kayaking disease as an antiplatelet

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8
Q

What’s the dose of breakthrough pain

A

1 tenth to 1 sixth of the total daily dose every 2-4 hrs when required

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9
Q

What can be given for opioid overdose?

A

Naloxone

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10
Q

What are the side effects of opioid!

A
Dry mouth 
Nausea and vomiting 
Constipation 
Sedation 
Euphoria
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11
Q

Which opioid side effects doesn’t improve with time?

A

Constipation

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12
Q

What side effects can occur with larger doses of opioids?

A

Hypotension
Muscle rigidity
Pupil constriction

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13
Q

What side effects can occur with long term use of opioid?

A

Hypogonadism
Adrenal insufficiency
HYPERALGESIA

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14
Q

When should opioids NOT be given?

A

Comatose patients
Paralytic ileus
Asthma attack and COPD

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15
Q

How often is standard release morphine given?

A

Every 4 hours

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16
Q

How often is MR morphine given?

A

Every 12/24 hours

17
Q

What is the maximum dose increase increments for morphine ?

A

1/3 to 1/2 every 24hrs

18
Q

How must the morphine dose be adjusted going from oral to IV/IM/SC?

19
Q

How must the morphine dose be adjusted going from oral to IV/IM/SC diamorphine?

20
Q

What is the mechanism of action for buprenorphine?

A

Partial opioid agonist

21
Q

How does naloxone affect buprenorphine?

22
Q

How must buprenorphine be separated with other opioids?

23
Q

What’s the risk with opioid naive patients and fentanyl

A

Respiratory depression

24
Q

When should fentanyl patients be removed IMMEDIATELY?

A

Breathing difficulties
Confusion
Dizziness

25
When must opioid dose be reduced 1/4 to 1/2 when switching to fentanyl?
Switching due to HYPERALGESIA
26
When is fentanyl unsuitable?
Acute pain | Rapidly changing pain
27
What advice should be given to patients with patches ?
Avoid exposure to external heat Apply to dry/ non hairy skin Rotate
28
What’s the dose of codeine codeine in adults?
30-60mg every 4hrs
29
What is the MHRA on codeine
Restricted use in children
30
What’s the dose for codiene in 12-18 yrs?
Max 240 a day for 3 days
31
Which opioids should not be given IV ?
Codeine | Dihydrocodiene
32
What patients should not take codiene ?
U18 with tonsillectomy’s | Breastfeeding
33
What are the additional effects of tramadol? What are the side effect implications?
Also affects serotonergic & noradrenergic pathways Risk of bleeding Lowers seizure threshold Psychiatric reactions
34
What are the benefits of tramadol?
Lower risk of respiratory depression
35
What are the interactions with tramadol?
Seizure threshold Serotonin syndrome Risk of bleeding