Chapter 4 BNF (Pain) Flashcards

1
Q

What’s best for MSK pain?

A

Non opioids

NSAIDs

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2
Q

What’s best for dental pain?

A

NSAIDs

Find cause

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3
Q

What can be offered for period pain?

A

Oral contraceptives
Antispasmodics
Non opioids

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4
Q

What can be offered for nerve compression by a tumour?

A

Dexamethasone

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5
Q

What dose aspirin should be given in medical emergencies?

A

Aspirin 300mg dispersinble or chewable. NOT Gastro resistant

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6
Q

What’s the aspirin dose for pain?

A

300-900mg every 4-6 hours

Max 4G

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7
Q

When can aspirin be used in under 16?

A

Kayaking disease as an antiplatelet

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8
Q

What’s the dose of breakthrough pain

A

1 tenth to 1 sixth of the total daily dose every 2-4 hrs when required

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9
Q

What can be given for opioid overdose?

A

Naloxone

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10
Q

What are the side effects of opioid!

A
Dry mouth 
Nausea and vomiting 
Constipation 
Sedation 
Euphoria
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11
Q

Which opioid side effects doesn’t improve with time?

A

Constipation

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12
Q

What side effects can occur with larger doses of opioids?

A

Hypotension
Muscle rigidity
Pupil constriction

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13
Q

What side effects can occur with long term use of opioid?

A

Hypogonadism
Adrenal insufficiency
HYPERALGESIA

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14
Q

When should opioids NOT be given?

A

Comatose patients
Paralytic ileus
Asthma attack and COPD

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15
Q

How often is standard release morphine given?

A

Every 4 hours

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16
Q

How often is MR morphine given?

A

Every 12/24 hours

17
Q

What is the maximum dose increase increments for morphine ?

A

1/3 to 1/2 every 24hrs

18
Q

How must the morphine dose be adjusted going from oral to IV/IM/SC?

A

1/2

19
Q

How must the morphine dose be adjusted going from oral to IV/IM/SC diamorphine?

A

1/3

20
Q

What is the mechanism of action for buprenorphine?

A

Partial opioid agonist

21
Q

How does naloxone affect buprenorphine?

A

Partially

22
Q

How must buprenorphine be separated with other opioids?

A

24 hrs

23
Q

What’s the risk with opioid naive patients and fentanyl

A

Respiratory depression

24
Q

When should fentanyl patients be removed IMMEDIATELY?

A

Breathing difficulties
Confusion
Dizziness

25
Q

When must opioid dose be reduced 1/4 to 1/2 when switching to fentanyl?

A

Switching due to HYPERALGESIA

26
Q

When is fentanyl unsuitable?

A

Acute pain

Rapidly changing pain

27
Q

What advice should be given to patients with patches ?

A

Avoid exposure to external heat
Apply to dry/ non hairy skin

Rotate

28
Q

What’s the dose of codeine codeine in adults?

A

30-60mg every 4hrs

29
Q

What is the MHRA on codeine

A

Restricted use in children

30
Q

What’s the dose for codiene in 12-18 yrs?

A

Max 240 a day for 3 days

31
Q

Which opioids should not be given IV ?

A

Codeine

Dihydrocodiene

32
Q

What patients should not take codiene ?

A

U18 with tonsillectomy’s

Breastfeeding

33
Q

What are the additional effects of tramadol? What are the side effect implications?

A

Also affects serotonergic & noradrenergic pathways

Risk of bleeding
Lowers seizure threshold
Psychiatric reactions

34
Q

What are the benefits of tramadol?

A

Lower risk of respiratory depression

35
Q

What are the interactions with tramadol?

A

Seizure threshold
Serotonin syndrome
Risk of bleeding