Chapter 5 BNF (Infectious Diseases) Flashcards
What are the signs and symptoms of an infection?
Fever Malaise Drowsiness in children Confusion in elderly Worsening renal failure
What risks are to be considered when offering antibiotics to elderly patients?
Risk of C. difficile
Renal and hepatic impairment
Which antibiotics are most likely to cause C.difficile?
Clindamycin (most)
Penicillins
Quinolones
2nd and 3rd gen cephalosporins
What’s first and second line in C.difficile?
Metronidazole
Oral vancomycin
Don’t give loperamide
What’s the treatment of Endocarditis?
Amoxicillin + low dose gentamicin
Add Flucloxacillin if Staphy
Add vancomycin if MRSA
Add Benzypenicillin if streptococcus
What’s the treatment of community acquired pneumonia? (Mild)
Amoxicillin, Clarithromycin, Doxycycline
7 days
What’s the treatment of community acquired pneumonia? (Moderate )
Amoxicillin + Clarithromycin
Or
Doxycycline
What’s the treatment of community acquired pneumonia? (Severe)
Benzypenicillin + Clarithromycin/Doxycycline
What’s the treatment of hospital acquired pneumonia for in patients less than 5 days in?
Co amoxiclav
Cefuroxime
7 days
What’s the treatment of hospital acquired pneumonia for in patients longer than 5 days?
Antipseudomonal penicillin
Broad spectrum cephalosporin
I Quinolone
What is the initial treatment of meningitis?
Benzypenicillin
Or
Cefotaxime
Or
chloramphenicol
What’s the treatment for osteomyelitis?
Flucloxacillin
Or
Clindamycin
Or
Vancomycin MRSA
What’s the treatment for impetigo? (Local) and (systemic)
Local: fusidic acid for 7 days,
muporicin (MRSA)
Systemic: Flucloxacillin for 7 days
What’s the treatment for cellulitis?
Flucloxacillin
What’s the treatment for animal bites?
Co amoxiclav
Metronidazole and doxycycline