Chapter 5 - Integumentary System Flashcards
The organs of the **integumentary system **include?
**skin **& accessory structures including hair, nails, glands, blood vessels, muscles and nerves
Dermatology
medical specialty for the diagnosis and treatment of disorders of the **integumentary system. **
**Skin **
aka?
location?
size?
subcutaneous membrane
covers body
largest organ of body by surface area & weight
**Skin **
area & weight
% of body weight
2 square metres (22 sq. feet)
4.5-5 kg (10-11 lb)
7%
**Skin **thickness
range & average
0.5-4.0 mm thick
thinnest on eyelids
thickest on heels
average = 1-2 mm
SKIN
(2) major layers
1) **epidermis - **outer, thinner layer; consists of epithelial tissue
2) **dermis - **inner, thicker layer
Beneath the dermis is?
a **subcutaneous (subQ) layer **(also called hypodermis)
which attaches the skin to underlying tissues & organs.
Important characteristics of the Epidermis
**(2) **
- composed of **keratinized **stratified squamous epithelium
contains 4 major types of cels
Epidermis
(4) major types of cells
1) keratinocytes
2) melanocytes
3) Langerhans cells
4) **Merkel cells **
Major cells of the epidermis: Keratinocytes
(90% of the cells)
**- **produce keratin (a tough fibrous protein that provides protection)
Major cells of the epidermis: Melanocytes
produce the pigment melanin that protects against damage by UV radiation
Major cells of the epidermis: **Merkel cells **
involved in immune responses, arise from red bone marrow
major cells of the epidermis: Merkel cells
function in sensation of touch along with adjacent tactile discs
The epidermis contains how many layers?
four major layers (thin skin)
five major layers (thick skin)
(5) layers of the epidermis
1) stratum corneum
2) stratum lucidum
3) stratum granulosum
4) stratum spinosum
5) stratum basale
Stratum Basale
aka stratum germinativum
deepest layer
continuous cell division occurs which **produces all other layers **
Stratum Spinosum
8-10 layers of keratinocytes
Langerham cells & projections of melanocytes present
Stratum Lucidum
present **only in thick skin **
(the skin of the fingertips, palms, and soles)
Stratum granulosum
includes keratohyalin and lamellar granules
consists of 3 to 5 layers of flattened keratinocytes undergoing apoptosis
marks transition between deeper metabolically active strata & dead cells of superficial strata
Stratum corneum
composed of many sublayers of flat, dead keratinocytes called corneocytes or squames that are *continuously shed and replaced *by cells from deeper strata;
constant friction can stimulate formation of a callus.
Formation of a callus
constant friction
Keratinization
the accumulation of more and more protective keratin, occurs as cells move from the deepest layer to surface layer
Dandruff
- an excess of keratinized cells shed from the scalp
Important characteristics of the Dermis
composed of connective tissue containing collagen & elastic fibers
contains 2 layers
(2) layers of the dermis
1) **Papillary **region
2) **Reticular **region
**Papillary **region
consists of?
containing?
outer region, consists of areolar (soft) connective tissue containing thin collagen, elastic fibers, dermal papillae (including capillary loops), corpuscles of touch & free **nerve endings **
**Reticular **region
deeper region,
consists of dense irregular connective tissue
containing collagen and elastic fibers, adipose cells, hair follicles, nerves, sebaceous (oil) glands, & sudoriferous (sweat) glands
**Striae **
stretch marks
- appear if the skin is stretched too much
Lines of Cleavage
tension lines” in the skin indicate the predominant direction of underlying collagen fibers