Chapter 5: Clinical: Biochemical, Physical, and Functional Assessment Flashcards
analyte
A substance whose chemical constituents are being identified and measured
basic metabolic panel (BMP)
A test that includes eight different measurements. It provides information about your metabolism
comprehensive metabolic panel (CMP)
A blood test with 14 different measurements. It is often used to evaluate liver function, kidney function, and nutrient levels
complete blood count (CBC)
A blood test that provides the count of the cells in the blood and description of the RBCs
differential count
A blood test that gives the relative percentage of each type of white blood cell and also helps to reveal abnormal white blood cell populations (eg, blasts, immature granulocytes, and circulating lymphoma cells in the peripheral blood)
urinalysis
Testing of the urine. Used as a screening or diagnostic tool to detect substances or cellular material in the urine associated with different metabolic and kidney disorders.
dehydration
Excessive loss of water and electrolytes often from vomiting; diarrhea; excessive laxative abuse; diuretics; fistulas; GI suction; polyuria; fever; excessive sweating; or decreased intake caused by anorexia, nausea, depression or limited access to fluids
edema
Overhydration. Occurs when there is an increase in the extracellular fluid volume. The fluid shifts from the extracellular compartment to the interstitial fluid
inflammation
A protective response by the immune system to infection, acute illness, trauma, toxins, many chronic diseases, and physical stress
positive acute-phase reactants
Inflammation markers that exhibit significant changes in serum concentration during inflammation. Positive acute phase reactants are upregulated, and their concentrations increase during inflammation.Positive acute phase reactants include procalcitonin, C-reactive protein, ferritin, fibrinogen, hepcidin, and serum amyloid A.
negative acute-phase reactants
Inflammation markers that exhibit significant changes in serum concentration during inflammation. Negative acute phase reactants are downregulated, and their concentrations decrease during inflammation.Negative acute phase reactants include albumin, prealbumin, transferrin, retinol-binding protein, and antithrombin
C-reactive protein (CRP)
A nonspecific marker of inflammation that may help estimate and monitor the severity of the illness
high-sensitivity CRP (hs-CRP)
A more sensitive measure of chronic inflammation seen in patients with atherosclerosis and other chronic disease
ferritin
A positive acute-phase protein, meaning that synthesis of ferritin increases in the presence of inflammation. Ferritin is not a reliable indicator of iron stores in patients with acute inflammation, uremia, metastatic cancer, or alcoholic-related liver diseases
erythrocyte sedimentation rate (ESR)
Reflects the rate at which RBCs settle into columns or stacks in saline or plasma within a given time period
albumin
Responsible for transport of major blood constituents, hormones, enzymes, medications, minerals, ions, fatty acids, amino acids and metabolites
prealbumin (PAB) aka transthyretin (TTHY)
Hepatic protein transported in the serum as a complex of retinol-binding protein and vitamin-A. It transports the thyroid hormones triiodothyronine and thyroxine (T4), along with T4-binding globulin.
retinol-binding protein (RBP)
A small plasma protein that does not pass through the renal glomerulus because it circulates in a complex with PAB
retinol
An animal form of Vitamin A. Retinol is converted from retinyl palmitate which is found in beef, chicken liver, eggs, fish liver oils, and dairy products including whole milk, whole mild yogurt and cottage cheese, butter, and cheese. (The plant based Vitamin A source is beta-carotene.) Vitamin A is essential to vision, especially night vision, bone and tooth development, reproduction, skin and mucous membranes
transferrin
A globulin protein that transports iron to the bone marrow for production of hemoglobin