Chapter 26: Upper Gastrointestinal Tract Disorders Flashcards
upper esophageal sphincter (UES)
The high-pressure zone located in between the pharynx and the cervical esophagus. The physiological role of this sphincter is to protect against reflux of food into the airways as well as prevent entry of air into the digestive tract
lower esophageal sphincter (LES)
Located at the distal end where it meets the stomach, is composed of a bundle of smooth muscle and functions to protect the reflux of gastric contents into the esophagus.
achalasia
Characterized by a failure of esophageal neurons, resulting in a loss of ability to relax the LES and have normal peristalsis
gastroesophageal reflux (GER)
A normal physiologic process that occurs several times a day in healthy infants, children, and adults. GER generally is associated with transient relaxation of the LES independent of swallowing, which permits gastric contents to enter the esophagus
gastroesophageal reflux disease (GERD)
A more serious, chronic form of GER, with symptoms or complications resulting from the reflux of gastric contents into the esophagus or beyond, and even into the oral cavity or lung
esophagogastroduodenoscopy (EGD)
A procedure that uses a fiberoptic endoscope to directly visualize and examine the esophagus, stomach, and duodenum to classify severity of disease
esophagitis
Inflammation of the esophagus
acid pocket
A layer of unbuffered, highly acidic gastric juice at the esophagogastric junction, ready to reflux due to the absence of peristaltic contraction in the proximal stomach
barrett’s esophagus (BE)
A precancerous condition in which the normal squamous epithelium of the esophagus is replaced by an abnormal columnar-lined epithelium known as specialized intestinal metaplasia
hiatal hernia
The esophagus passes through the diaphragm by way of the esophageal hiatus or ring. The attachment of the esophagus to the hiatal ring may become compromised, allowing a portion of the upper stomach to move above the diaphragm
nissen fundoplication
The most commonly performed antireflux surgery. The fundus or top portion of the stomach is wrapped 360 degrees around the lower esophagus and sutured in place to limit reflux
esophagectomy
An operation to remove a portion of the esophagus.
dysphagia
Swallowing difficulty
gastric pull-up
A procedure that involves removal of a segment of or the entire esophageal tract and replacing it with the stomach tissue
odynophagia
Painful swallowing
parietal cells
Acid-producing cells
dyspepsia
Indigestion