Chapter 5 Flashcards
What does cell division allow?
A single-celled fertilized egg to grow into an organism with trillions of cells.
What are somatic cells?
Body cells that continue to undergo cell division even as an adult.
What is apoptosis?
Programmed cell death. It decreases the number of cells when cells age and no longer function well. It also plays an important role in preventing cancer.
What is the cell cycle?
The orderly sequence of stages with cell division.
What is interphase?
What cell does between times of division.
What are the 3 stages of interphase?
G1: stage before DNA synthesis.
S: DNA synthesis
G2: Stage after DNA synthesis.
Describe G1.
Cell doubles its organelles and accumulates material. Mostly, cell is in growth phase and if DNA is damaged, cell will undergo apoptosis.
Describe S stage.
At start, each chromosome consists of one DNA molecule, called chromatid. Each chromatid makes an exact copy of itself, and after DNA replication, each chromosome now consists of two sister chromatids.
Describe G2.
The cell synthesizes proteins for cell division. Cell also checks if there is any damage that happened when sister chromatids were made. If so, apoptosis occurs.
What is the mitotic stage?
When cell undergoes division. Usually a very short period of time.
What is mitosis?
Division of the nucleus.
What is cytokinesis?
Division of the cytoplasm.
When does cytokinesis occur?
Just after mitosis, the two daughter cells become two identical cells.
What are caspases?
The enzymes responsible for apoptosis as they are unleashed by external and internal signals.
Describe internal signals.
Ensure the stages follow one another in the normal sequence and properly completed.
Describe external signals.
Tell the cell whether or not to divide.
Describe the 3 checkpoints that control the cell cycle.
G1: stops if DNA is damaged
G2: stops if DNA did not finish replicating
M: stops if chromosomes are not going to be properly distributed.
The checkpoints are critical for preventing cancer development.
What are chromosomes composed of?
Chromatin.
What is a diploid (2N)?
Cells that have two of each type of chromosome.
What is a haploid (1n)?
Cells have half the diploid number of chromosomes.
Describe the overview of mitosis.
Nuclear division in which chromosome number stays constant, one 2n cell becomes two 2n cells. DNA replication produces duplicated chromosomes. Each duplicated chromosome is composed of two sister chromatids held together by a centromere.
What is mitosis?
Nuclear division that forms two daughter nuclei with the same number of chromosomes and the same kind of chromosomes.
Are daughter cells the same as parental cells?
Yes.
What does a spindle do?
Brings an orderly distribution of chromosomes to the daughter cell nuclei.
Describe prophase.
Nuclear membrane disappears, centrosomes migrate, spindle fibres appear. Chromatin condenses and chromosomes become visible. (Each is composed of 2 sister chromatids) and the chromosomes have no particular orientation.
Describe prometaphase.
Centromeres attach to spindle fibres, centrosomes have migrated to either end.
Describe metaphase.
Spindle fully forms and consists of poles, asters, and fibres. Chromosomes line up at metaphase plate.
Describe anaphase.
Centromeres divide, and sister chromatids are moved to opposite poles by fibres.