Chapter 4: Tissue Level of Organization Flashcards
Epithelial Tissues
A group of cells that usually have a common origin in an embryo and function together
Tissues
Epithelial Tissues
covers body surfaces and lines hollow organs, body cavities and ducts and also forms glands
Allows the body to interact with both internal and external environment
Connective tissue
Protects and supports the body and its organs
Various types of tissues bind organs together, store energy reserves as fat, and help provide the body with immunity to disease causing organisms
Muscular Tissue
is composed of cells specialized for contraction and generation of forces
In the process, muscular tissue generates heat that warms the body
Nervous Tissue
detects changes in a variety of conditions insides and outside of the body and responds by generating electrical signals called nerve action potentials that activate muscular contractions and glandular secretions
Cell Junctions
Contact points between plasma membranes of tissue cells; 5 types
The five types of cell junctions
- Tight junctions
- adherens junctions
- desmosomes
- hemidesmosomes
- Gap junctions
Tight junctions
- fuse togeher the outer surfaces of adjacent plasma membranes to seal off passageways between adjacent cells
- web like strands of transmembrane proteins
eg. stomach or bladder cells are adhered with tight junctions to prevent leakage of contents into other tissues
Adherens junctions
- contain plaque - a dense layer of proteins on the inside of the plasma membrane that attaches both to the membrane proteins and to microfilaments of the cytoskeleton
- it forms an adhesion belt
- transmembrane glycoproteins join the cells
What are the transmembrane glycoproteins that join the cells in an adheren junction; they link together on the outside of the cell membranes o-o-o-o-o
Cadherins
Adhesion belts
formed by adherens junctions in epithelial cells and encircle the cell.
help epithelial surfaces resist separation during various contractile activities
eg. digestive tract contractions
Desmosomes
contain plaque and have transmembrane glycoproteins (cadherens) that extend into the intracellular space between adjacent cell membranes and attach cells to one another
however, the plaque of desmosomes does not attach to microfilaments, but rather intermediate filaments inside the cell
Found in skin and heart tissue cells
spot weld junctions
Hemidesmosomes
Look like desmosomes but do not link adjacent cells; instead anchor cells to the basement membrane
transmembrane proteins in hemidesmosomes are integrins rather than cadherins
When do integrins attach to in hemidesmosomes?
Intermediate filaments on the inside of the plasma membrane made of protein keratin
On the outside of the cell, they adhere to the protein laminin on the basement membrane
Gap Junctions
Connect neighboring cells via membrane proteins called connexions that make connexons (tiny fluid filled tunnels)
Intercellular gap between them, not completely connected
Allows passage of ions, nutrients and wastes between avascular tissues cells like lens and cornea of the eye
Allows communications
Epithelial Tissue (vs)
Many cells tightly packed with little or no extracellular matrix
No blood vessels
Usually forms surface layers and isn’t covered by another tissues (one expection is the blood vessel since blood is a tissue)
Connective Tissue
Large amount of extravellular material that separates cells that are usually widely scattered
Most have significant networks of blood vessels
Why is epithelial tissue always found adjacent to connective tissue?
Because it lacks blood vessels and forms surfaces and the blood vessel rich connective tissues enables it to make exchanges with blood
Describe epithelial tissue (epithelium)
cells arranged in a continuous sheet in either single or multiple layers
Two general patterns of epithelial cells in the body
- covering and lining various surfaces
- forming the secreting portion of glands
What is the function of epithelial tissues?
- protects, secretes, absorbs and excretes
Apical Surface
(aka free surface) outermost / most superficial layer
faces the body surface, cavity, the lumen of an internal organ or tubular duct
may contain cilia or microvilli
Lateral epithelial cell surfaces
Face adjacent cells on either side
may contain cell junctions (not hemidesmosome)
Basal surface of epithelial cells
Opposite the apical surface - the deepest layer
Adhere to extracellular materials like the basement membrane
Contain hemidesmosomes
Basement membrane
thin extracellular layer that consists of two layers
two layers of basement membrane
- basal lamina
- Reticular lamina