Chapter 3 Review Q&A Flashcards
***Infants are more susceptible to significant losses in TBW
Kidney are not mature enough to deal with fluid losses
Infants are more susceptible to change in water because they have
High metabolic rate
Greater total body surface area in proportion to total body size
**Obesity creates a greater risk for dehydration in people because
Adipose cells contain little water because Fat is WATER REPELLANT
There is a lot/little body water in adipose tissue
Little
***Water movement between the intracellular fluid compartment and the extracellular fluid compartment is primarily function of
OSMOTIC forces
***In addition to OSMOSIS, what is the force involved in the movement of water between the plasma and interstitial fluid space?
HYDROSTATIC PRESSURE
Water moves between the plasma and interstitial fluid through the forces of ________and _______Accross the ________ ________
Osmosis
Hydrostatic pressure
Capillary membrane.
What does oncotic pressure do?
encourage water to cross the barrier of capillaries to enter the circulatory system.
**Venous obstruction is a cause of edema because of an increase in which pressure?
CAPILLARY HYDROSTATIC PRESSURE
Venous obstruction can increase the hydrostatic pressure of fluid in the ________enough to cause fluid to escape into the ________Space
Capillaries; interstitial spaces
***At the arterial end of capillaries , fluid moves from the intravascular space into the interstitial space because the
Capillary HYDROSTATIC pressure is HIGHER than the capillary ONCOTIC PRESSURE
***Low plasma albumin causes edema as a result of a reduction in which
PLASMA ONCOTIC pressure
What is the ONLY thing that leads to a decreased in plasma oncotic pressure?
Decrease ALBUMIN
***Secretion of the ADH hormone and the perception of thirst are stimulated by?
INCREASED IN PLASMA OSMOLALITY
***Thirst activates osmoreceptors by an increase in which in BLOOD PLASMA?
OSMOTIC PRESSURE
Thirst is experienced when water loss equals ____% of body weight or when ______ ______Increases
2%; Osmotic pressure
What are the osmo-receptors? what are they stimulated by ?
Neurons in the hypothalamus stimulated by INCREASED IN OSMOTIC PRESSURE
***It is true that natriuretic peptides: { in/de BP, water and sodium retain/excrete)
Decreased BP and Increase sodium and water EXCRETION
What are the 3 different natriuretic peptides and where are they produced?
Atria natriuretic peptide : atria of myocardium
BRAIN natriuretic peptide (BNP) produced in ventricles of myocardium
URODilatin: Produced in the kidneys.
***When changes in total body water are accompanied by proportional change in electrolytes, what type of alteration occurs?
ISOTONIC
**Which enzymes is secreted by the JUXTAGLOMERULAR Cells of the kidney when circulating blood volume is reduced?
RENIN
RENIN is released in response to (para/symp) _________ nerve stimulation and (incre/decr) __________ perfusion to the renal vasculature.
Sympathetic
decreased
**What mechanism cause hypernatremia?
HYPERSECRETION OF ALDOSTERONE
Cushing syndrome can also cause hypernatremia because of the oversecretion of ________hormone which also leads to oversecretion of _________
ACTH; ALDOSTERONE
For hypernatremia, during cardiac arrest, the inappropriate administration of ________Saline solution such as _____ ______may lead to ___________
Hypertonic
Sodium bicarbonate
Hypernatremia
***What causes the clinical manifestations of confusion, convulsion, cerebral hemorrhage and coma in hypernatremia?
HIGH SODIUM in the blood vessels pulls water OUT OF THE BRAIN CELLS, causing BRAIN CELLS TO SHRINK.
Water follows
SODIUM
***Vomiting induced metabolic alkaloiss, resulting in the loss of chloride causes
RETENTION of sodium bicarbonate to maintain the anion balance
When vomiting with the depletion of ECF and chloride causes ACID LOSS, renal compensation is
NOT effective
Loss of electrolytes such as Na+, K+, H+ and Cl- stimulate a paradoxic response by the ______. What does the kidney do?
kidneys ; it increases sodium and bicarbonate reabsorption with the excretion of HYDROGEN
***The PATHOPHYSIOLOGIC process of edema is related to which mechanism
LYMPHATIC OBSTRUCTION
***Insulin is used to treat HYPERKALEMIA because it:
Transport potassium from the blood to the cell along with
What does insulin do to regulate potassium?
stimulate the sodium-potassium pump.
***A major determinant of the resting membrane potential necessary fro the transmission of nerve impulse is the ration between
INTRACELLULAR and EXTRACELLULAR POTASSIUM
*** During acidosis (ELEVATED HYDROGEN IONS), the body compensates for the increase in serum HYDROGEN IONS by shifting hydrogen ions into the cell in exchange for which electrolyte
POTASSIUM
therefore, because of the shift of electrolyte during acidosis: ACidosis and ______ often occur together
HYPERKALEMIA
**2 Causes of hyperkalemia include?
Renal Failure and Addison disease
*** In hyperkalemia, what change occurs to the cell’s resting membrane
HYPOPOLARIZATION (depolarization)
**The Calcium and phosphate balance is influenced by which three substances?
Parathyroid hormone
Calcitonin
Vitamin D
** It is true that kussmaul respiration indicate
a compensatory mechanism is needed to correct metabolic acidosis.
**Chvostek and trousseau sing indicate which electrolyte imbalance
HYPOCALCEMIA
*** An excessive use of magnesium-containing antacids and aluminum containing antacids can results in
HYPOPHOSPHOTEMIA
What are the most common cause of hypophosphatemia
Intestinal malabsorption
Increased renal excretion of phosphate
**the most common cause HYPERMAGNESEMIA is
Renal Failure
***Physiologic pH is maintained at approximately 7.4 because bicarbonate (HCO3) and carbonic acid exist in a rtion of
20:1
***Which arterial pH will initiate the formation of ammonium (NH4) from ammonia (NH3) referred to ACADEMIA, in the tubular lumen of the kidney
7.25
***Two thirds of the body’s water is found in its
INTRACELLULAR FLUID Compartments
One third of the body’s water is in
extracellular fluid
What are the 2 main ECF compartments
Interstitial
Intravascular
***It is true that when insulin is administered
the liver increases its potassium levels
*** Increased capillary hydrostatic pressure results in edema because of
SODIUM and WATER RETENTION
INCREASED CAPILLARY HYDROSTATIC PRESSURE is a result of
VENOUS OBSTRUCTION
SODIUM AND WATER RETENTION