BLOOD Vessel & Hemodynamics Flashcards
Vessel walls structures
Know structures.
Arteries
Carry blood away from the heart
Atherosclerosis
Fats
Elastic arteries
Conducting arteries.
Exchange of oxygen
Capillaries.
Capillary bed blood flow
Contolled by metarteriole/ Precapillary sphincters.
Capillary bed blood flow
Controlled by metarteriole/ Pre-capillary sphincters.
Types of capillaries: Continuous
Occurs in most tissues
Types of capillaries:Fenestrated:
Kidneys small intestine, choroid plexus.
Cilliary bodies
Types of capillaries: Sinusoids
Found in liver, bone marrow, and spleen
Sinusoids
irregular filled blood spaces.
Capillary exchanged (3)
Simple diffusion
Transcytosis
Bulk flow.
Transcytosis
Large lipid insoluble molecules cross capillaries in vesicles via transcytosis
Filtration is
pressure driven movement of fluid and solutes from blood capillaries into interstitial fluid.
Filtration is promoted by
Blood hydrostatic pressure (BHP ) and Interstitial fluid osmotic pressure
Reabsorption is
Pressure driven movement of fluid and solutes from interstitial fluid into blood capillaries
Left over fluids
Goes over to lymph and then to SUBCLAVIAN SINUS
Net filtration: 2 forces
Hydrostatic Pressure
Colloid Osmotic pressure.
Increase capillary filtration
increase BP
Increased permeability
Increase capillary filtration
increase BP permeability
Poor venous return
Increase histamine
kidney failure
Decreased capillary reabsorption can be due to ________, ______, ______, ________, _____ there is low ______Pressure related to _______ ______
Hypoproteinemia, cirrhosis, burns, famine, kidney disease
Decrease oncotic pressure
Blood albumin
Veins
lower pressure 10mmhg
Thinner wall, less muscular and elastic tissue
Expand easily, have high capacitance
Venules two types:
Post capillary venules
Muscular venules
Venous sinuses; what are they?
Veins within walls.
Blood flow
Volume of blood flowing through the tissue in a given time
Perfusion
Rate of blood flow per given mass of tissue
Important for delivery of nutrients and oxygen and removal
metabolic wastes
CO determinants
SV and HR
Co also can be determine
MAP / R
MAP
Measurements taken at intervals
BP
Force of blood exerts against vessel wall.
BP is determined by
CO
Blood volume
Vascular resistance.
Factors that affect or increased BP
Increases SV and HR
Increase SBP
Regulation of BP and Flow
Local control
Neural
Hormonal Control –>
Metabolic Theory of autoregulation
Tissue inadequately perfused
Wastes accumulate= Vasodilation
Atrial nutrieretic peptide
Increase sodium excretion == decreased BP
ADH comes from
Posterior Pituitary
Increased water retention
Vasoconstriction
BP increased
Epi and norepinelphrie
Catecholamines released from
Epi and norepinephrine
Catecholamines released from
Shock and homeostatis
Inadequate CO that results in failure of the CV system
Cell membranes dysfunction: what happens to metabolism?
cell metabolism is abnormal
Homeostatic responses to SHOCK
Activation of RAAS
Secretion of ADH
Activation fo SNS
Signs and Symptoms of shock
Homeostatic mechanisms bring about recovery
Decreased BP tri
What is an an anastomose? Function?
Arteries that do not form an anastomosis are called__________
Union of the branches of 2 or more arteries supplying the same region of the body
This provides an alternate route for blood flow
“end arteries”
Elastic arteries (“conducting” arteries)
Large diameter
More elastic fibers, less smooth muscle
Function as pressure reservoirs
Muscular arteries (“distributing” arteries)
Medium diameter
More smooth muscle, fewer elastic fibers
Distribute blood to various parts of the body
Elastic expansion and recoil of the aorta & its main branches Functions?
Maintaines steady flow of blood during diastole;
Decrease stress on small arteries
Smoothes out pressure fluctuations
Elastic aorta and arteries STRETCH During
Ventricular contraction
Elastic aorta and arteries RECOIL During
Ventricular Relaxation
In general a blood vessel has 3 layers:
Tunica interna (a.k.a. tunica intima) Innermost layer, adjacent to lumen(AL)
Tunica media (SMEF) Middle layer, smooth muscle and elastic fibers
Tunica externa (around tissue) Outermost layer, adjacent to surrounding tissue
Parts of the capillary? (outer to inner) BEL
Basement membrane
Endothelium
Lumen
Parts of the Veins (outer to inner) TSBLE
Tunica externa Smooth Muscle (TUNICA MEDIA) Basement membrane Lumen Endothelium
Parts of the ARTERIES (outer to inner)
TETIBE
Tunica EXTERNA External Elastic Lamina Tunica Media (smooth muscle) Internal elastic Lamina Basement membrane Endothelium (Tunica INTERNA)
The walls of the arteries are _______ which allows them to do what?
smooth muscle in the tunica media regulate________
elastic; which allows them to absorb the pressure created by ventricles of the heart (creating a pressure resevoir)
- diameter
What layer in the arteries regulate diameter
ELASTIC SMOOTH MUSCLE IN THE TUNICA MEDIA
BP ____ with age: arteries become _________
rises ; less distensible
Name 3 arterial sense organs
Carotid Bodies
Carotid Sinuses
Aortic Bodies
Carotid Sinuses : What do they cause?
Sensitive to ?
Dilation in wall of internal carotid arteries. (sensitive to pressure change)
Monitor BP - signaling brainstem
HR decrease and vessels dilate.
FUNCTION: Carotid bodies : oval bodies near carotids (cluster of _______) monitor ________
adjust _______ to stabilize _________
oval bodies near carotids (cluster of chemoreceptors)
blood chemistry
respiratory rate to stabilize pH, CO2, and O2
Aortic bodies found were
Function ?
walls of aorta
same as carotid bodies
Arterial sense organ innervation 2 nerves
Vagus
GLOSSOPHARYNGEAL
Aortic bodies innervated by (think VA)
Vagus nerve
Carotid bodies innervated by (think GC)
Glossopharyngeal nerve
Capillaries are
microscopic vessels that connect arterioles and venules