Chapter 3 Flashcards

1
Q

Communication between neurons is PRIMARILY ________

A

chemical

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2
Q

Specialized gap between neurons

A

synapse

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3
Q

Discovered narrow gap between neurons

A

Ramon y Cajal

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4
Q

Demonstrated that communication between one neuron & the nxt differs from communication along single axon

A

Charles Scott Sherrington

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5
Q

Automatic muscular responses to stimuli

A

Reflexes

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6
Q

Circut from sensory neuron to muscle response

A

Reflex Arc

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7
Q

Repeating stimuli w/in a brief time have a cumulative effect

A

Temporal summation

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8
Q

the cell that RECEIVES a msg

A

Postsynaptic Neuron

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9
Q

Cell that DELIVERS the transmission

A

Pre-Synaptic Neuron

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10
Q

Graded depolarization; occurs when sodium ions enter the cell; that decays over time & space; Discovered by Eccles

A

Excitatory Postsynaptic Potential (EPSP)

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11
Q

Synaptic inputs from various locations combine their effects of a neuron.

A

Spatial Summation

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12
Q

How did Sherrington discover this?

A

Pinch a dog’s foot; one time=nothing; but several pinches did

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13
Q

Ordinarily Occur together…

A

Temporal summation & spatial summation

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14
Q

Hyperpolarizes

A

increases the negative charge w/in the cell, moving it further from the threshold & decreasing the probability of an action potential

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15
Q

Occurs when the synaptic input selectively opens the channel for potassium ions to leave the cell or for chloride ions to enter the cell

A

Inhibitory Postsynaptic Potential (IPSP)

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16
Q

The importance of Sherrington’s work

A

led to researcher’s being able to show how nervous system was wired & make a diagram

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17
Q

Peridoic reproduction of action potentials even w/out synaptic input

A

spontaneous firing rate

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18
Q

1st to suggest that synapses operated by using chemicals (adrenaline) as means of transmitting signals (British)

A

T.R. Elliot

19
Q

Won the Nobel Prize for his work w/chemical synapses; 1st to convincingly demonstrate that communicate across the synapse occurs via chemical means (German)

A

Otto Loewi

20
Q

Chemicals released by one neuron that affect a second neuron

A

Neurotransmitter

21
Q

Acids containing an amine group (NH2)

A

Amnio Acids

22
Q

Chains of amino acids

A

Neuropeptides

23
Q

Chemical similar to amino acid, except that NH2 group has been replaced by N(CH3) group (one member “family”)

A

Acetylcholine

24
Q

Neurotransmitters containing one amine group (NH2), formed by a metabolic changed in certain amino acids

A

Monoamines

25
Chemical category that includes adenosine & several of its derivatives
Purines
26
Nitric Oxide & possibly others
Gases
27
epinephrine, norepinephrine (adrenaline), dopamine
catecholamines
28
tiny packets that store high concentrations of neurotransmitters
Vesicles
29
A chemical that breaks down excess lvls of some neurotransmitters
MAO (monoamine oxidase)
30
Release of neurotransmitter in bursts from presynaptic terminal into synaptic cleft
exocytosis
31
Why does a neuron release a combo of neurotransmitters instead of just one?
the combo makes the neuron's msg more complex, such as brief excitation followed by slight but prolonged inhibition.
32
Occur at one type of receptor; channels controlled by neurotransmitter are transmitter-gated or ligand-gated channels; begin quickly & last for very brief period of time
Ionotropic effects
33
Initiates a series of metabolic reactions; slower & longer lasting than inotropic effects;
Metabotropic effects
34
For vision & hearing, the brain needs rapid, quickly changing info, the kind that this brings
Ionotropic synapses
35
better suited for more enduring effects such as taste, smell & pain; also important for many aspects of arousal, attention, pleasure, & emotions (functions that arise more slowly & last longer than a visual or auditory stimulus)
Metabotropic synapses
36
Often described as neuromodulators- have several porperties that distinguish them from neurotransmitters
neuropeptides
37
chemicals that are secreted by gland or other cell & conveyed by the blood to other organs
Hormones
38
Glands that produce hormones
Endocrine glands
39
Consists of anterior pituitary & posterior pituitary
Pituitary gland
40
after it activates a receptor, it's broken down by enzyme (acetylcholinesterase) into acetate & choline
Acetylcholine
41
In certain brain areas, presynaptic neuron takes up most of the released neurotransmitter molecules intact & reuses them
Reuptake (occurs thru transporters)
42
Detect the amount of neurotransmitter released & inhibit further synthesis & release after it reaches a certain lvl
autoreceptors
43
special purpose synapses that operate electrically
electrical synapses
44
contact between membrane of one neuron w/membrane of another
gap junction