Chapter 29 Flashcards
Pregnancy with Diabetes Mellitus
Considered high risk
Key to an optimal outcome is strict glycemic control
Effects of Diabetes Mellitus
Fetal growth acceleration, rise in placental hormone levels, insulin resistance
At birth, maintenance of normal maternal glucose levels is essential to reduce neonatal hypoglycemia
Metabolic Changes Associated with Pregnancy
GLUCOSE CROSSES THE PLACENTA, INSULIN DOES NOT
INSULIN NEEDS INCREASE DURING THE FIRST TRIMESTER
ABOUT 10% OF PREGNANCIES HAVE PREEXISTING DM
Neonatal Effects of Diabetes Mellitus
Hypoglycemia
Hypocalcemia
Hyperbilirubinemia
Respiratory distress syndrome
Postpartum Care of Pregestational Diabetes Mellitus
FIRST 24 HOURS, INSULIN REQUIREMENTS DROP SUBSTANTIALLY
Risk of hemorrhage due to uterine distention
Risk Factors for Gestational Diabetes Mellitus
Overweight Maternal age older than 25 Previous birth outcome often associated with GDM GDM in previous pregnancy History of abnormal glucose tolerance Family history of diabetes Member of a high-risk ethnic group
GDM Antepartum Care
Diet, exercise, self-monitoring of blood glucose, pharmacologic therapy, fetal surveillance
GDM Intrapartum Care
Blood glucose monitored hourly in labor
Infusion of regular insulin
GDM Postpartum Care
Will return to normal glucose levels after birth
Likely to recur in future pregnancies
Hyperemesis Gravidarum
EXCESSIVE, PROLONGED VOMITING ACCOMPANIED BY WEIGHT LOSS, ELECTROLYTE IMBALANCE, NUTRITIONAL DEFICIENCIES, AND KETONURIA
Initial Care for Hyperemesis Gravidarum
IV therapy for correction of fluid and electrolyte imbalances
Medications
Enteral or parenteral nutrition as a last resort
Therapeutic Management of Hyperemesis Gravidarum
Promethazine (Phenergan)
Diphenhydramine (Benadryl)
Histamine-receptor antagonists
Gastric acid inhibitors
Metoclopramide (Reglan)
Ondansetron (Zofran)
Hyperthyroidism in Pregnancy
Rare in pregnancy, usually caused by Graves’ disease
Heat intolerance, diaphoresis, fatigue, anxiety, emotional lability, tachycardia, weight loss, goiter, high pulse rate
Drug therapy is primary treatment
Hypothyroidism in Pregnancy
Severe hypothyroidism is often associated with infertility and increased risk of miscarriage
Weight gain, lethargy, decrease in exercise capacity, cold intolerance
LEVOTHYROXINE is medication regimen