CHAPTER 22: Small Gram-negative coccobacilli: Haemophilus, Brucella, Francisella, Yersinia and Bartonella

Question 1

Septicaemia, meningitis and osteomyelitis are usually associated with type __ infection of Haemophilus influenzae

Answer 1

B

Question 2

Many H. influenzae express which mechanism of resistance and are resistant to which medication

Answer 2

β-lactamase

Ampicillin

Question 3

Medications used for H. influenzae infection

Answer 3

Co-amoxiclav, clarithromycin, tetracycline or trimethoprim

Question 4

Severe H. influenzae infections are treated with a ___________

Answer 4

β-lactam-stable cephalosporin

Question 5

Haemophilus specie that is transmitted sexually and causes painful, irregular, soft genital ulcers (chancroid)

Answer 5

H. ducreyi

Question 6

Treatment for H. ducreyi infections

Answer 6

Azithromycin, ceftriaxone or a fluoroquinolone

Question 7

Aerobic or capnophilic organisms that require serum-containing medium to grow and have goats, cattle and pigs as main hosts

Answer 7

Brucella spp

Question 8

Fever caused by Brucella spp

Answer 8

Undulant fever

Question 9

A chronic ____________ infection may develop without treatment, which may resolve or continue to give symptoms, often accompanied by psychiatric complaints, for many years

Answer 9

Brucella

Question 10

Optimal treatment and duration for Brucella infection

Answer 10

Tetracycline for 1 month

Question 11

________ should be added for patients with complications to Brucella infection

Answer 11

Streptomycin

Question 12

Pathogen of rodents and deer found in North America that causes systemic infection gives a syndrome that
resembles typhoid, with 5–10% mortality

Answer 12

Francisella tularensi

Question 13

Patients with iron-overload syndromes are especially susceptible to _________

Answer 13

Yersinia enterocolitica

Question 14

This organism can cause mesenteric adenitis that mimics appendicitis.

Answer 14

Yersinia pseudotuberculosis

Question 15

_______ are small Gram-negative bacteria that can invade host red blood cells, epithelial and bone marrow cells.

Answer 15

Bartonella

Question 16

____________ is responsible for cat-scratch disease, endocarditis and bacilliary angiomatosis, a febrile illness associated with a red, papular rash that is commonly found in patients with AIDS

Answer 16

B. henselae

Question 17

Fever caused by Bartonella quintana

Answer 17

Trench fever

Question 18

_________, which is transmitted by lice, causes a relapsing febrile illness found in severely disadvantaged individuals

Answer 18

B. quintana

Question 19

Fever caused by Bartonella bacilliformis

Answer 19

Oroya fever

Question 20

Organism that causes an acute febrile haemolytic
anaemia or mild fever with body pain, nausea and headache that is transmitted by sandflies and found only in Peru and neighboring countries

Answer 20

Bartonella bacilliformis