CHAPTER 21: Neisseria and Moraxella

Question 1

Gram-negative diplococcus that adheres to the genitourinary epithelium via pili, then invades the epithelial layer and provokes a local acute inflammatory response

Answer 1

Neisseria gonorrhea

Question 2

Medications for N. gonorrhea

Answer 2

Ceftriaxone
Spectinomycin
Fluoroquinolone

Question 3

Infection is most common in the winter, with epidemics occurring every 10–12 years

Answer 3

Neisseria meningitis

Question 4

Most common N. meningitis serogroup that causes infection

Answer 4

Group B

Question 5

Pathogenicity of N. meningitis

Answer 5

Antiphagocytic polysaccharide capsule
Lipo-oligosaccharide
IgA protease

Question 6

N. meningitis hijacks which receptor to cross the blood brain barrier

Answer 6

ß2-adrenoreceptor

Question 7

Meningococci cross mucosal epithelium by _______

Answer 7

Endocytosis

Question 8

Central gum metal gray hue in Meningococcal meningiti

Answer 8

Fulminant purpura

Question 9

Prophylaxis for meningococcal meningitis

Answer 9

Rifampicin

Ciprofloxacin

Question 10

Gram-negative coccobacillus is usually a commensal of the upper respiratory tract, associated with otitis media, sinusitis and lower respiratory tract infection in children or patients with chronic pulmonary disease

Answer 10

Moraxella catarrhalis