chapter 19 - blood Flashcards
what are the functions of blood?
transportation, regulation, and protection
what type of tissue is blood?
connective tissue
what is the liquid portion of blood?
plasma
what is the solid portion of blood?
formed elements
what are red blood cells (most), white blood cells, and platelets?
formed elements in blood
what does plasma consist of?
water (most), solutes (proteins, electrolytes, gases, nutrients, regulatory substances, and waste)
what are most of the solutes in blood plasma?
proteins
what produces the proteins in blood plasma?
the liver
what are albumin, fibrinogen, and globulin?
plasma proteins
what is a plasma protein that maintains osmotic pressure?
albumin
what is a plasma protein that helps stop bleeding (clotting)?
fibrinogen
what is a plasma protein that protects against virus and bacteria?
globulins
what is another name for RBCs?
erythrocytes
what transports oxygen from the lungs to cells and transport carbon dioxide from cells to lungs?
RBCs
what is another name for white blood cells?
leukocytes
what protects from invading pathogens and foreign substances?
leukocytes
what is another name for platelets?
thrombocytes
what promote blood clotting when there is damage?
thrombocytes
what is the water inside of cells called?
intercellular
what is the water outside of cells called?
extracellular
what is the fluid that is outside of organs and blood vessels?
interstitial fluid
what is the process by which formed elements of blood develop?
hemopoiesis or hematopoiesis
what are blood cells in red bone marrow formed from?
pluripotent stem cells
what is a reticulocyte?
an immature red blood cell
what happens as a reticulocyte matures?
the nucleus is ejected
what transports oxygen to cells and carbon dioxide from cells?
red blood cells
what is hemoglobin?
oxygen carrying protein
what are huge cells that splinter into thousands of fragments?
megakaryocytes
what helps stop blood loss from damaged vessels by clotting?
platelets
what is a fragment of megakaryocytes enclosed by a piece of the plasma membrane?
platelet (thrombocyte)
what are neutrophils, lymphocytes, monocytes, eosinophils, and basophils?
types of white blood cells
what are the most common white blood cells, first to the scene, phagocytic?
neutrophils
what are the main phagocytes of white blood cell, become macrophages?
monocytes
what are white blood cells that enhance inflammation and secrete histamine (increasing blood flow)?
basophils
what are white blood cells that combat inflammation, (parasites)?
eosinophils
what is a sequence of responses that stops bleeding (hemorrhage)?
hemostasis
what are the three mechanisms that reduce blood loss?
vascular spasm, formation of platelet plug, and blood clotting (coagulation)
what is a vascular spasm?
smooth muscle fibers constrict, reducing blood loss (minutes to hours)
what are the three steps to the formation of a platelet plug?
- Platelet adhesion
- Release reaction
- Platelet aggregation (plug the hole)
what is an enzyme produced by extrinsic and intrinsic pathways?
prothrombinase
which pathway in blood clotting is fast?
extrinsic pathway
which pathway in blood clotting is slower?
intrinsic pathway
what is it called when prothrombinase is converted into prothrombin and thrombin?
the common pathway
what is the common pathway?
the second stage of blood clotting
what happens in the third phase of blood clotting?
thrombin converts fibrinogen into fibrin
what is fibrin?
insoluble fibers
what does thrombin speed up the formation of?
extra prothrombinase and activates platelets
what is a foreign substance?
antigen
what blood type has “universal donors”?
O individuals (no antigens)
what is the ABO blood group determined by?
the presence or absence of A and B antigens
which blood type has “universal recipients”?
AB individuals (neither anti-A nor anti-B antibodies)
what blood type is determined by the presence of absence of A and B antigens?
ABO blood group
what is the Rh system?
RBC with Rh antigen are Rh+ and without Rh antigen are Rh-
what happens when a Rh+ fetus develops in the uterus of an Rh- woman?
hemolytic disease
what is a group of cancers of the bone marrow which results in uncontrollable division of WBCs?
lukemia
what is the total blood volume occupied by RBCs?
hematocrit
what is a condition where the oxygen-carrying capacity of blood is reduced due to low RBCs?
anemia
what is the result of a low iron intake?
anemia
what is a condition of abnormally high hematocrit?
polycythemia
what is caused by a genetic defect that produces abnormal hemoglobin?
sickle-cell disease
what causes blockages in blood vessels?
sickle-cell disease