Chapter 18 - BLOOD Flashcards
Total blood volume in adult WOMAN
70 mL/kg
Total blood volume in adult MAN
80 mL/kg
________ is a suspension of cellular elements in plasma.
Whole blood
If you spin down a sample of blood containing an anticoagulant for __________, the bottom fraction contains FORMED ELEMENTS (RBCs, WBCs and platelets).
5 minutes at 10,000 g
The top fraction is ____________.
Blood plasma
The _____ having the highest density are at the bottom of the tube.
RBCs
WBCs and platelets form a WHITISH GRAY layer - the ________ - between the RBCs and plasma.
Buffy coat
The __________ is the fraction of the total column occupied by RBCs.
Hematocrit
The normal hematocrit for ADULT WOMEN.
40%
The normal hematocrit for ADULT MEN.
45%
The hematocrit in the NEWBORN is ____ and falls to ____ at 2 months of age, from which time it rises during development to reach adult values at puberty.
55%
35%
The __________ is a measure of concentration of RBCs, not of total body red cell mass
Hematocrit
Total RBC volume is ______ body weight in the ADULT WOMAN
28 mL/kg
Total RBC volume is ______ body weight in the ADULT MAN.
36 mL/kg
______ is a pale-white watery solution of electrolytes, plasma proteins, carbohydrates and lipids.
Plasma
Pink-colored plasma suggests the presence of hemoglobin caused by _______ and release of hemoglobin into the plasma.
Hemolysis (lysis of RBCs)
A brown-green color may reflect elevated ________ levels.
Bilirubin
Plasma can also be cloudy in __________.
Cryoglobulinemias
Plasma proteins at a normal concentration of 7.0 g/dL account for a colloid osmotic pressure or oncotic pressure of _________.
25 mmHg
Principal plasma proteins are:
Fibrinogen
Albumin
Globulins
Other coagulation factors
The molecular weights of plasma proteins range up to _______ kDa.
970 kDa
The plasma concentration of albumin ranges from _____________.
3.5 to 5.5 g/dL
Total plasma albumin pool of the body.
135 g
Albumin is synthesized by the liver at a rate of ________ body weight per day and due to CATABOLISM, has a half-life in the circulation of _________.
120 mg/kg
20 days