Chapter 16 Flashcards
a region of DNA that transcribes a single primary transcript
transcription unit
a cluster of prokaryotic genes organized into a single transcription unit and their associated regulatory sequences
operon
DNA sequence involved in the regulation of a gene or genes to which a regulatory protein binds to control the transcription of the gene or genes
regulatory sequences
a DNA regulatory sequence that controls transcription of an operon
operator
DNA-binding protein that binds to a regulatory sequence and affects the expression of an associated gene or genes
regulatory protein
a regulatory protein that prevents the operon genes from being expressed
repressor
a regulatory protein that controls the expression of 1 or more genes
activator
gene that encodes a protein that has a function other than gene regulation
structural gene
gene that encodes a protein that regulates the expression of a structural gene or genes
regulatory gene
concerning regulation of gene expression in bacteria, a molecule that turns on the transcription of the genes in an operon
inducer
operon whose expression is increased by an inducer molecule
inducible operon
key regulatory molecule involved in positive gene regulation of the lac operon
CAP (catabolite activator protein)
a regulatory protein that controls the expression of 1 or more
activator
region in the promoter of the lac operon and in the promoters of a large number of other operons that control the catabolism of many sugars to which activated catabolite activator protein (CAP) binds, thereby enabling RNA polymerase to bind and transcribe the operon’s structural genes
CAP site
operon whose expression is prevented by a repressor molecule
repressible operon
in the regulation of gene expression in bacteria, a regulatory molecule that combines with a repressor to activate it an shut off an operon
corepressor
in eukaryotes the proteins required for RNA polymerase to initiate transcription or that regulate that process. one class of it recognizes and binds to the promoter in the area of the TATA box and then recruit RNA polymerase
transcription factor
upstream of a eukaryotic gene, a region containing regulatory sequences -promoter proximal elements- for transcription called promoter proximal elements
promoter proximal region
regulatory sequence within the promoter proximal region, a region upstream of the promoter of a eukaryotic proteincoding gene. regulatory proteins bind to promoter proximal elements and stimulate or inhibit the rate of transcription initiation
promoter proximal elements
in eukaryotes, a region at a significant distance from the beginning of some proteincoding genes that contain regulatory sequences to which regulatory proteins bind to stimulate or inhibit the rate of transcription initiation over and above that seen for regulatory events at the promoter proximal elements
enhancer
in eukaryotes, a protein that binds to the promoter of a gene in the area of the TATA box and recruits and orients RNA polymerase II to initiate transcription at the correct place
general transcription factor
combination of general transcription factors with RNA polymerase II
transcription initiation complex
a regulatory protein that controls the expression of 1 or more genes
activators