Chapter 13 Blood System Flashcards
albumin
protein in blood; maintains the proper amount of water in the blood.
antibody (Ab)
protein (immunoglobulin) produced by lymphocytes in response to bacteria, viruses, or other antigens. An antibody is specific to an antigen and inactivates it.
antigen
substance (usually foreign) that stimulates the production of an antibody.
basophil
white blood cell containing granules that stain blue; associated with release of histamine and heparin.
bilirubin
orange-yellow pigment in bile; formed by the breakdown of hemoglobin when red blood cells die.
coagulation
blood clotting
colony-stimulating factor (CSF)
protein that stimulates the growth and proliferation of white blood cells (granulocytes).
differentiation
change in structure and function of a cell as it matures; specialization
electrophoresis
method of separating serum proteins by electrical charge.
eosinophil
white blood cell containing granules that stain red; associated with allergic reactions
erythrocyte
red blood cell. there are about 5 million per microliter or cubic millimeter of blood.
erythropoietin (EPO)
hormone secreted by the kidneys that stimulates red blood cell formation.
fibrin
protein threads that form the basis of a blood clot.
fibrinogen
plasma protein that is converted to fibrin in the clotting process.
globulin
plasma protein; alpha, beta, and gamma (immune) globulins are examples.
granulocyte
white blood cell with numerous dark-staining granules: eosinophil, neutrophil, and basophil.
hemoglobin
blood protein containing iron; carries oxygen in red blood cells.
hemolysis
destruction or breakdown of blood (red blood cells).
heparin
anticoagulant found in blood and tissue cells.
immune reaction
response of the immune system to foreign invasion.
immunoglobulin
protein (globulin) with antibody activity; examples are IgG, IgM, IgA, IgE, IgD.
leukocyte
white blood cell
lymphocyte
mononuclear leukocyte that produces antibodies.
macrophage
monocyte that migrates from the blood to tissue spaces. As a phagocyte, it engulfs foreign material and debris.
megakaryocyte
large platelet precursor cell found in the bone marrow.
monocyte
leukocyte with one large nucleus. It is a cell that engulfs foreign material and debris. Monocytes become macrophages as they leave the blood and enter body tissues.
mononuclear
pertaining to a cell (leukocyte) with a single round nucleus; lymphocytes and monocytes are mononuclear leukocytes.
neutrophil
granulocytic leukocyte formed in bone marrow. It is a phagocytic tissue-fighting cell. Also called a polymorphonuclear leukocyte.
plasma
liquid portion of blood; contains water, proteins, salts, nutrients, hormones, and vitamins.
plasmapheresis
removal of plasma from withdrawn blood by centrifuge. Collected cells are retransfused back into the donor. Fresh-frozen plasma or salt solution is used to replace withdrawn plasma.
platelet
small blood fragment that collects at sites of injury to begin the clotting process.
prothrombin
plasma protein; converted to thrombin in the clotting process.
reticulocyte
immature erythrocyte. a network of strands (reticulin) is seen after staining the cell with special dyes.
Rh factor
antigen on red blood cells of Rh-positive (RH+) individuals. The factor was first identified in the blood of a rhesus monkey.
serum
Plasma minus clotting proteins and cells. Clear, yellowish fluid that separates from blood when it is allowed to clot. It is formed from plasma, but does not contain protein-coagulation factors.
stem cell
unspecialized cell that gives rise to mature, specialized forms. A hematopoietic stem cell is the progenitor for all different types of blood cells.
thrombin
enzyme that converts fibrinogen to fibrin during coagulation.
thrombocyte
platelet.
bas/o
base
chrom/o
color
coagul/o
clotting
cyt/o
cell
eosin/o
red, dawn, rosy