Chapter 12 - Phytonutrients Flashcards

1
Q

Phytochemicals (aka phytonutrients)

A

Non-nutrient component of plants with physiological effects on humans

Lower cholesterol

Reduce risk of cancer

Lower blood pressure

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2
Q

Eating fruits and vegetables can

A

cut your cancer risk in half

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3
Q

cabbage

A

= no cancer

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4
Q

Protective fruits and vegetables

A

Lettuce

Leafy greens

Onions

Carrots

Cabbage family

Citrus

Broccoli

Potatoes

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5
Q

Beta-carotene hypothesis

A

Beta-carotene protects against cancer without conversion to retinol

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6
Q

Anti-oxidant hypothesis

A

suggests that anti-oxidant compounds protect the body from oxidative damage that could lead to cancer

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7
Q

Examples of anti-oxidants

A

Vitamins C & E

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8
Q

Sources of beta-carotene

A

Yellow and orange fruits and vegetables

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9
Q

Tomatoes get their color from

A

lycopene

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10
Q

Sources of lutein

A

Dark leafy greens are rich in a carotenoid called lutein

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11
Q

Where are lutein and lycopene found?

A
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12
Q

How many carotenoids in nautre?

A

500 carotenoids in nature

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13
Q

Chemoprevention

A

Prevention of cancer by use of phytochemicals

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14
Q

Diet rich in tomatoes

A

Lowers risk of prostate cancer

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15
Q

Carcinogenesis

A

The process of the development of cancer

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16
Q

Carcinogens

A

Chemicals that damage DNA and lead to the development of cancer

17
Q

lung cancer -

A

asbestos workers

18
Q

Liver cancer -

A

vinyl chloride

19
Q

Nitrates - nitrosamines

A

Can contribute to cancer risk

20
Q

Spoiled foods leads to…

A

stomach cancer

21
Q

aflotoxins

A

example of molds toxins

leads to liver cancer

22
Q

Examples of foods that naturally have carcinogens present

A

Bracken fern and sassafras

23
Q

Three stages of the development of cancer

A
  1. initiation
  2. promotion
  3. progression
24
Q

Apoptosis

A

The process in a normal cell that seperates it from a cancer cell

Programmed cell death

25
Initiation
First stage in carcinogenesis, marked by DNA damage, which produces an initiated cell, which is neither normal nor cancerous
26
Promotion
Second stage in carcinogenesis, marked by more DNA damage, which takes the cell from being an initiated cell to being a cancer cell
27
Progression
Final stage in carcinogenesis, which produces a tumor
28
Malignant
Cancerous, as in a tumor 2 characteristics: invasive and metastasize
29
Metastasize
To spread metastatically they grow into surrouding tissues, invading them, spreading into nearby organs
30
Metastasis
The spread of the cancer to distant locations
31
Phase I enzymes
create or activate procarcinogens into actual carcinogens
32
Receptors
Site on a cell that binds to a hormone
33
Lignans
Lower blood levels of estrogen
34
Indoles
induce higher levels of enzymes that lower amounts of an estrogen precursor
35
Angiogenesis
the development of blood vessels blocked by genistein
36
Ecology
The interaction between individual organisms and between organisms and their environment
37