Chapter 11.4 - Nervous System Flashcards
soma
cell body of the neuron, contains nucleus
dendrites
receive signals from previous neurons
Axon
part of the neuron that sends signals to the axon terminal and passed onto next neuron
Axon hillock
connects axon to cell body, summated graded potentials
myelin sheaths are formed by ____ in the CNS
oligodendrocytes
myelin sheaths are formed by ___ in the PNS
Schwann cells
how does myelin sheath allow action potentials to travel faster down the axon?
insulated the axon from undergoing ion exchange, can only occur at nodes of ranvier
saltatory propagation/conduction
action potential jumps from one node of ranvier to the next
When a neuron is stimulated, it is ____ and the membrane becomes ___ ____
depolarized; less negative
When a neuron is stimulated, __ ___ ___ are opened
Na+ gated channels
When the threshold potential is reached,:
more Na+ gated channels open, membrane potential becomes more positive creating action potential
Once the membrane potential reaches its max potential:
the neuron will repolarize
How does neuron repolarize?
K⁺ gated channels open up, causing K⁺ outflow out of the neuron
Hyperpolarization
Membrane potential goes lower than resting state, makes it more challening for another AP to fire
refractory period can be ___ or ___
absolute or relative
Absolute refractory period
a second stimulus cannot generate another action potential no matter how powerful it is. Na+ gated channels remain inactivated
relative refractory period
sufficiently powerful stimulus can cause an action potential to occur - voltage gated sodium channels are no longer inactivated, but the neuron is still hyperpolarized
When an AP reached the end of the presynaptic axon: (4)
- voltage gated calcium channels open
- Ca²⁺ ions to flow into the presynaptic neuron
- triggers synaptic vesicles to fuse with the membrane
- via exocytosis release the neurotransmitters they contain into the synaptic cleft
EPSPs
generated by excitatory nt’s; cause NA+ gated gates to open, neuron fires AP
IPSPs
generated by inhibitory neurotransmitters; cause K⁺ ion gates to open, which results in a K⁺ outflow, more hyperpolarized, harder to fire AP
EPSPs and IPSPs are:
graded potentials
True or false: graded potentials always cause AP to fire
false - they vary in magnitude.
an action potential will fire down the axon if:
the sum of EPSPs and IPSPs is higher (less negative) than the threshold potential
APs are:
all or nothing (either it fires or not at all)