Chapter 10 Lesson 1 Flashcards
What are the stages of the cell cycle?
G0, G1, G2, S (Synthesis), and M (Mitosis)
When the cell cycle is complete, what are the three things that can happen to the daughter cells?
1) Divide
2) Differentiate
3) Die
What three phases make up interphase in the cell cycle?
G1, G2, and S (Synthesis)
What are some examples of stimulitory protiens?
- Growth Factors
- ACP/C
- CDK
- Cyclins
- Proto-oncogens
What is an example of an inhibitory protien?
P53
What is the role of stimulitory protiens?
Cause the cell to pass its progress through the cell at critical points
What is the role of inhibitory protiens?
Cause the cell to stop its progress through the cell at critical points
What do proto-oncogenes do?
Code for stimulating protiens
What do tumor suppressor genes do?
Code for inhibitory protiens
How can tumor suppressor genes cause cancer?
If both of your versions are switched off, for example in P53, if DNA is mutated then gene p53 stops division
What requirements have to be met at the G1 checkpoint?
- No DNA damage
-Sufficient resources
What requirements have to be met at the G2 checkpoint?
- No DNA damage
- Chromosome set complete, enough cell components
What requirements have to be met at the S (Synthesis) checkpoint?
- No errors during DNA replication
What requirements have to be met at the M (Mitosis) checkpoint?
- All sister chromatids are attached to mitotic spindle