Chap 3 Flashcards
Cell Structure
Cell Membrane
Boundary providing passage for ions, cellular components, and knowledge into cytoplasm.
Cluster Designation (CD)
monoclonial Antibodies that indicate cells and markers of disease states.
Cytoplasm (Plasm)
Metabolic activities location.
Golgi Complex
Involved in the formation of: Gamma Globulins, Lysosomes, Specific Granules (SGs), and Other Cellular Components
Ribosomes
RNA, Synthesis proteins
Endoplasmic Reticulum (ER)
Comm system W/ nucleus (Smooth or Rough).
Mitochondria
furnish cell W/ energy
Lysosomes
Granules W/ hydrolytic enzymes
Nucleus
*Chromatin
*Nucleolus/Nucleoli
*Nuclear Envelope
Chromatin
Dark staining chromosomal material composed of DNA and proteins.
(DNA regulates all cell funcions).
Nucleolus/Nucleoli
Pale staining patches rich in RNA or DNA.
# of nucleoli corresponds to the amount of protein synthesis.
Nuclear Envelope
Double membrane around nucleus.
Chromatin appearance varies depending on?
Activity
Euchromatin
Dispersed and lightly stained
Unwound or Loosely twisted
Transcriptionally Active
Heterochromatin
Condensed and deeply stained
Tightly twisted or folded
Transcriptionally Inactive
General Morph changes in Cell maturation are?
Baso Plasm-> Less Baso
Reduces in size
Nucleus size reduces
Chromatin condenses
Nuclear to Cytoplasmic Ratio (NCR)
ratio of the size of nucleus to the size of the cytoplasm.
NCR decreases with
Maturity
NCR increases with
Immature cells
Stain used for WBC differentiating and RBC Morph is?
Wright’s Stain
Eosin Stain
Acid Stain that stains red
Methylene
Basis stain that stains shades of blue
Mecahnical causes of cell death?
In prep of blood smears
Physiological causes of cell death?
Necrosis or Apoptosis
Pyknosis
Degeneration of a cell and part of apoptosis, or effects of chemo.
Pyknosis causes the cell to?
Shirk in size and condense the chromatin to a solid structureless mass/masses. Bright pink plasm and dark purple nucleus.
Karyorrhexis
Nuclear necrosis, causing nucleus to rupture and chromatin disintegrates into formless granules.