Chap 14

Question 1

List 2 clinical conditions that would indicate the need for BM studies?

Answer 1

Hematologic Diseases and Systemic Disease

Question 2

What is an example of a hematologic disease?

Answer 2

Anemia, Erythrocytosis, Polycythemia,
Leukopenia.

Question 3

If someone had a hematologic disease, what would the appearance of their cells in PB circulation be?

Answer 3

Abnormal or Immature cells

Question 4

Examples of Systemic Disease?

Answer 4

Solid malignant tumors elsewhere in the body, Infections known as fevers of unknow origin (FUO), Histiocytic diseases.

Question 5

Adult BM aspiration sites in adults?

Answer 5

Posterior Superior Iliac Crest
Ocassionally Sternum or Anterior Iliac Crest.

Question 6

<2yrs old site of BM aspiration?

Answer 6

Anterior tibia

Question 7

Older children, but younger than adolescence BM aspiration site?

Answer 7

Sines of the lumbar vertebral

Question 8

Specimen preparation for examination?

Answer 8

Make direct smear from aspirate
Make crush smear from BM spicules
Place extra into anti-coag tubes

Question 9

Laboratorian roles during BM aspiration?

Answer 9

Provide equipment and perform the preliminary exam and processing.

Question 10

Needle used for BM aspiration?

Answer 10

Jamshidi Trephine needle 8 or 11 gauge.

Question 11

M:E Ratio

Answer 11

The myeloid and erythroid cell ratio between all Grans and their precursors and all NRBC precursors.

Question 12

What part of the specimen does hitology get to process?

Answer 12

Clot in the syringe and the biopsy

Question 13

Who receives the other specimens obtained(I.E. viral, fungal, or routine culture specimens)?

Answer 13

Microbiology

Question 14

Paperwork and package specimens are sent out to?

Answer 14

Reference Lab

Question 15

The direct apsirate smear from the syringe is evaluated for?

Answer 15

Cell Morph W/ Wright’s Stain.

Question 16

Particle(Crush) Smear is evaluated for?

Answer 16

Cellularity and the relationship of cells to each other.

Question 17

The concentrated buffy coat (M:E) smer is evaluated for?

Answer 17

Hematopoietic cells and the M:E ratio.

Question 18

The term used to describe when the marrow cannot be aspirated?

Answer 18

Dry tap

Question 19

Touch Prep of biopsy means?

Answer 19

A dry tap has occured

Question 20

Reference Range for M:E Ratio?

Answer 20

4:1 is Normal

Question 21

How does the BM cellularity and content change as we age?

Answer 21

Red marrow decreases and adipose tissue replaces it.