Chap 1 Flashcards
Intro Unit 1 Begininng.
Hematology
the study of RBCs, WBCs, and PLTs (the blood cells).
Functions of the Hemo Lab:
Confirm a physician’s clinical impression of a possible hematological disorder
Establish a diagnosis or rule out a diagnosis
Detect an unsuspected disorder
Monitor the effects of radiation or chemotherapy
Hemostasis
a series of cellular and plasma-based mechanisms that seal wounds, repair vessel walls, and maintain vascular patency (unimpeded blood flow), mainly PLTs.
Hematopoiesis
the continuous, regulated process of renewal, proliferation, differentiation, and maturation of all blood cell lines.
3 formed elements in blood:
RBCs, WBCs, PLTs
Blood Functions:
- Transport Medium
- Removes
Waste/Waste
products
*Cellular Defense - Prevents blood loss
Plasma
55% of a centrifuged specimen.
Composition:
Water (92%)
Soulutes (8%)
Albumin, Globulins,
Fibrinogen, Others( Electrolytes, Hormones, Vitamins, Lipids, Salts, Enzymes, and Carbs).
Plasma Functions:
- Transport Medium for nutrients and metabolites.
- Immune Defense.
*Coag
Serum
Fluid portion of the blood that remains after the blood has clotted; blood cells, coag factors, and coag control proteins, consumed in clot formation, essentially absent. Clear liquid of WBCs and PLTs (buffy coat). 1%
RBC Mass
the RBCs fall to the bottom of a centrifuged specimen.
44% of blood.
Whole Blood
The blood specimen with no components removed.
Coagulation’s preferred specimen
*Fresh plasma would be ideal.
*Volume Reqs may necessitate use of frozen or preserved pooled plasma, preserved aliquots from proficiency agencies, or QC materials.
Hematology’s preferred specimen
PT anticoagulated whole blood or preserved QC materials.
WBC Reference Ranges
To the nearest tenth in decimal form (7.7x10^3/uL).
To the nearest hundredth if no decimal
(7,700).
Adult WBC
3.6-11.0x10^3/ uL
