Ch.89 Osteochondrosis Dissecans Flashcards
What is DOD and what diseases are included in this
Developmental Orthopaedic Disease
All noninfectious orthopaedic deranged developments of growing young horses
Includes:
Wobblers
Collapse of cuboidal bones
Angular limb deformaties
Flexural limb deformaties
Subchondral bone cysts
Physitis
What is OC latens
Focal chondronecrosis of the resting zone of growth cartilage with adjacent vascular necrosis
What is OC manifesta
Focally impaired endochondral ossification and cartilage retention
What is OC dissecans
Cleft formation through the necrotic cartilage
JOCC refers to
Developmental orthopaedic diseases related to immature joint or growth plate
ie epiphyseal/metaphyseal development disorders
OCD includes what diseases
Cuboidal bone disease and other failures of the immature skeleton but not wobblers, flexural limb deformities or angular limb deformities
What is endochondral ossification
Cartilage remodelling
Followed by calcification
and successive remodelling
into boney trabeculae
Ossification of the cartilage ring around the ossification centre in the epiphyses of the long bones, first takes place where?
Border of the physis
and perimeter of the epiphysis
High levels of calcium or phosphorus have been associated with OC
Phosphorus - 4 times the recommended
Early foals vs late foals predilections sites for OC
Early - tarsocrural j.
Late - femoropatellar j
How has Insulin been linked to OC
Insulin and its derivatives IGF-I and IGF-II act as mitogens for chondrocytes and stimulate chondrocyte survival or suppressing apoptosis
OC affected foals have higher or lower IGF-I activity
Lower
Mixed housing ie in at night out by day has been associated with higher incidents of OC true or false
True
What is chondrification
Obliteration of cartilage canals during ossification
Patent cartilage canals are not seen in the proximal phalanx after what age
3 weeks
