Ch.59 Intraocular Surgery Flashcards
What % of horses with ERU lose vision or had the eye removed
28% lost vision
12% had eye removed
(15% euthanised)
Prevelance of ERU in USA vs UK
USA 2-25%
UK 0.3%
ERU is characterised by
Repeated episodes of intraoccqular inflammation
The uveal tract is composed of what structures
Iris
Ciliary body
Choroid
Breakdown of the blood aqueous barrier causes what
-Vascular dilation
-Increased vascular permeability
leading to
-increased levels of protein and cells within the aqueous vitreous humor
What is the Tyndall effect
increased protein within humor scatters light aka aqueous flare
Hallmark of uveitis
Primary inflammatory mediator in ERU
Prostaglandins
Leukotrienes
Effect of prostaglandins in ERU
Hyperemaia
Hypotony
Constrict iris and ciliary muscles - miosis and pain
What is posterior synechia and what causes it
Prolonged miosis and increased protein levels causes adhesions between posterior bridal epithelium and the anterior lens
Effects of posterior synechia
Extensive synechia can obstruct the pupil causing blindness
Can block fluids behind iris causing anterior bowing - iris bombe
Secondary glaucoma
Most frequent inciting cause of ERU
Leptospira interrogans