Ch. 6 Pedigree Analysis and Applications Flashcards
True or False: When you see a pedigree, you should just try something out and start writing letters down
False
What is the pedigree solving order?
checked for Y-linked
check for recessive/dominant
check fo X-linked/autosomal
What do you check in for Y-linked?
only males are affected
if a son is affected, his father must be affected
if a father is affected, all his sons must be affected
What is true if a pedigree is recessive?
unaffected parents can have an affected kid
if both parents are affected, all kids must be affected
What is true if a pedigree is dominant?
if a child is affected, a parent must be affected
two affected parents can have unaffected kids
True or False: when testing if it is x-linked or autosomal, you already know if it is dominant/recessive
True
Do you test for x-linked or autosomal?
x-linked
True or False: x-linked is a pattern
True
If you know it is recessive, how do you test for X-linked?
all affected mothers have affected sons
If it is dominant, how do you know test for x-linked?
if a father is affected, all his daughters must be affected
if a mother is unaffected, all her sons must be unaffected
If it passes the x-linked test, it is…
x-linked
If it fails the x-linked test, it it…
autosomal
If you can’t perform the X-linked test…
it can be both, look for other indicators
In very large samples, what is true?
x-linked dominant has more females affected
x-linked recessive has more males affected
recessive skips generations
Can we use the properties for large samples in our pedigrees?
no