Ch. 6 Pedigree Analysis and Applications

Question 1

True or False: When you see a pedigree, you should just try something out and start writing letters down

Answer 1

False

Question 2

What is the pedigree solving order?

Answer 2

checked for Y-linked
check for recessive/dominant
check fo X-linked/autosomal

Question 3

What do you check in for Y-linked?

Answer 3

only males are affected
if a son is affected, his father must be affected
if a father is affected, all his sons must be affected

Question 4

What is true if a pedigree is recessive?

Answer 4

unaffected parents can have an affected kid
if both parents are affected, all kids must be affected

Question 5

What is true if a pedigree is dominant?

Answer 5

if a child is affected, a parent must be affected
two affected parents can have unaffected kids

Question 6

True or False: when testing if it is x-linked or autosomal, you already know if it is dominant/recessive

Answer 6

True

Question 7

Do you test for x-linked or autosomal?

Answer 7

x-linked

Question 8

True or False: x-linked is a pattern

Answer 8

True

Question 9

If you know it is recessive, how do you test for X-linked?

Answer 9

all affected mothers have affected sons

Question 10

If it is dominant, how do you know test for x-linked?

Answer 10

if a father is affected, all his daughters must be affected
if a mother is unaffected, all her sons must be unaffected

Question 11

If it passes the x-linked test, it is…

Answer 11

x-linked

Question 12

If it fails the x-linked test, it it…

Answer 12

autosomal

Question 13

If you can’t perform the X-linked test…

Answer 13

it can be both, look for other indicators

Question 14

In very large samples, what is true?

Answer 14

x-linked dominant has more females affected
x-linked recessive has more males affected
recessive skips generations

Question 15

Can we use the properties for large samples in our pedigrees?

Answer 15

no