Ch 29 Alterations of Leukocyte, Lymphoid and Hemostatic Function

Question 1

Lymphadenopathy

Answer 1

Enlarged lymph nodes

Question 2

Neutropenia

Answer 2

Lower than normal neutrophil count in the blood

Question 3

Pancytopenia

Answer 3

Lower than normal blood counts of white blood cells, red blood cells and platelets

Question 4

Higher than normal white blood cell count

Answer 4

Leukocytosis

Question 5

Lower than normal white blood cell count

Answer 5

Leukopenia

Question 6

higher than normal blood counts of neutrophils, eosinophils and basophils

Answer 6

Granulocytosis

Question 7

Lower than normal blood counts of neutroohils, eosinophils, and basophils

Answer 7

Granulocytopenia

Question 8

Complete absence of neutrophils, eosinophils and basophils in the blood

Answer 8

Agranulocytosis

Question 9

All types of leukemia are characterized by uncontrolled ____ of white blood cells in the ____ ____ that thereby ____ the amount and function of erythrocytes and platelets

Answer 9

production; bone marrow; decreases

Question 10

HIT

Answer 10

heparin induced thrombocytopenia

PF4 from activated platelet binds to heparin, this complex is bound to antibodies that causes a release in substances that promote clotting

Question 11

Leukemia vs. Lymphoma

Answer 11

Leukemia- cancer of blood forming cells

Lymphoma- cancer of lymphatic tissue

Question 12

Lymphocytic leukemia vs. myelogenous leukemia

Answer 12

LL- from lymphoid cell line, produce B+T lymphocytes and NK cells
ML- from myeloid cell line, produce granulocytes, monocytes, erythrocytes and platelets

Question 13

Splenomegaly vs. hypersplenism

Answer 13

Splenomegaly- enlarged spleen

Hypersplenism- overactive spleen

Question 14

Philadelphia chromasome

Answer 14

Genetic translocation between chromosomes 9 and 22 that creates a mutant protein implicated in CML and other types of leukemia