Ch 12 Cancer Biology

Question 1

Malignant tumor arising from connective tissue

Answer 1

Sarcoma

Question 2

Malignant tumor of glandular epithelium

Answer 2

Adenocarcinoma

Question 3

Malignant tumor of fat cells

Answer 3

Liposarcoma

Question 4

Malignant tumor of skeletal muscles

Answer 4

Rhabdomyosarcoma

Question 5

Benign tumor of fat cells

Answer 5

Lipoma

Question 6

Benign tumor of smooth muscle

Answer 6

Leiomyoma

Question 7

Malignant bone tumor

Answer 7

Osteogenic sarcoma

Question 8

Benign tumor of skeletal muscle

Answer 8

Rhabdomyoma

Question 9

Malignant tumor arising from epithelial tissue

Answer 9

carcinoma

Question 10

Primary liver cancer

Answer 10

Hepatocellular carcinoma (HCC)

Question 11

True of False?

Progression from a benign polyp to a malignant tumor requires multiple mutations.

Answer 11

True.

It takes 4-7 mutations.

Question 12

Different CA cells from the same tumor can metastasize to (the same location/different locations) because tumors are (heterogeneous/homogeneous) in their cellular composition.

Answer 12

different locations

heterogeneous

Question 13

(Acute/chronic) inflammation predisposes to development of CA.

Answer 13

Chronic

Question 14

Characteristics of a Benign Tumor

Answer 14

• well-differentiated cell appearance
• slow rate of growth
• low mitotic index
• slight vascularization
• no ability to metastasize

Question 15

Characteristics of a Malignant Tumor

Answer 15

• poorly differentiated cell appearance
• rapid rate of growth
• high mitotic index
• may become invasive
• able to metastasize

Question 16

The immune system (cell-mediated) is important in protecting against cancers caused by specific _______ infections.

Answer 16

viral

Question 17

Survival of malignant tumors is facilitated by tumor-associated __________ that secrete __________ and other factors that assist cancer cell survival and proliferation.

Answer 17

macrophages

cytokines

Question 18

Stem cells and cancer cells are ale to divid infinitely because they make the enzyme ___________.

Answer 18

telemorase

Question 19

True or False?

Cancer is often detected early due to the pain that it causes.

Answer 19

False.

Cancer generally does not cause pain until the tumor is so large that it puts pressure on nerves or causes a lot of tissue destruction or inflammation.

Question 20

Descibe how chemotherapy threatment may cause temporary anemia.

Answer 20

Chemotherapy destroys some of the cells in the bone marrow that make RBCs, causing the patient to not make enough RBCs, causing chemotherapy induced anemia (CIA).