ch 11 Flashcards

1
Q

what is synovial fluid

A

located in friction areas between joints (think knee)
–> fluid fills joint cavity

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2
Q

formation of synovial fluid

A

ultrafiltration of plasma from synovial membrane

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3
Q

composition of synovial fluid

A

glucose and uric acid concentrations are equal to that of plasma

total protein and immunoglobulin concentration are 1/4-1/2 that of plasma

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4
Q

volume of synovial fluid

A

less than 3.5
–> depends on joint cavity size

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5
Q

normal synovial fluid (color, viscosity, WBC count, glucose concentration)

A

pale yellow
high
less than 200
equal to plasma

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6
Q

group 1 noninflammatory synovial fluid (color, viscosity, WBC count, glucose concentration)

A

yellow
high
less than 3000
equal to plasma

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7
Q

conditions associated with group 1

A

osteoarthritis, osteochondritis, traumatic arthritis

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8
Q

group II inflammatory synovial fluid (color, viscosity, WBC count, glucose concentration)

A

yellow-white
low
2000-100000
less than plasma level

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9
Q

associated conditions with group 2

A

gout, rheumatoid arthritis lupus

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10
Q

group II septic (color, viscosity, WBC count, glucose concentration)

A

yellow-green
low
10,000-100000
less than plasma

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11
Q

associated conditions with group 3

A

bacterial, fungal infection

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12
Q

group IV hemorrhagic (color, viscosity, WBC count, glucose concentration)

A

red-brown
decreased
less than 5000
equal to plasma

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13
Q

associated conditions with group 4

A

trauma blood disease (sickle cell)

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14
Q

how is synovial fluid removed

A

arthrocentesis (sterile needles to remove fluid from joint)

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15
Q

are there any circumstances when synovial specimens should be rejected

A

no

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16
Q

collection of synovial fluid

A

tube 1: no anticoagulant (chemical)
tube 2: anticoagulant (microscopic)
tube 3: sterile anticoagulant (microbiological)

17
Q

which anticoagulants are used

A

EDTA and sodium heparin because they do not form crystals

18
Q

what temp should synovial fluid be analyzed

A

room temp

19
Q

physical examination

A

pale yellow/colorless = normal
red/brown = trauma
green = infection
milky = arthritis or lupus

20
Q

what changes clarity of synovial fluid

A

WBCs, RBCs, crystals, fat, rice bodies

21
Q

should synovial fluid form clots

A

no

22
Q

cell count (microscopic exam)

A

RBCs = less than 2000
–> increase = trauma
WBCs = less than 200
–> increase = bacterial

23
Q

monosodium urate monohydrate

A

looks like needles
associated with gout arthritis

24
Q

calcium pyrophosphate dihydrate

A

loos like rod
associated with pseudogout

25
Q

cholestorol

A

looks flat and rectangular
associated with chronic arthritic conditions

26
Q

corticosteroid

A

seen after steroid injection

27
Q

chemical examination

A

glucose –> equivalent concentrations
total protein –> increase = inflammation
uric acid –> equivalent

28
Q

gram stain

A

sensitivity depends on organism (does not require culture to grow)