Cell Structure Flashcards
How do proteins know where they are supposed to go in the cell?
They have built in postal codes within their amino acid sequence
Hydrophobic amino acids go to?
The endomembrane
Charged amino acids go to?
The mitochondria
No signalling sequence amino acids go to?
The cytosol
The path from signal in the amino acid to protein
The signal sequence gets recognized by another protein, which guides the ribosome to the rough ER. The protein will then be made through the RER membrane into the ER lumen
The endomembrane system is comprised of? (NEGLVVP)
- Nuclear envelope
- Endoplasmic reticulum
- Golgi apparatus
- Lysosomes
- Vesicles and vacuoles
- Plasma membrane
What are the functions of the endomembrane system? (STMMD)
- Protein synthesis
- Protein transport
- Metabolism
- Mouvement of lipids
- Detoxifying the cell
What is the endoplasmic reticulum?
The flattened membrane sacks called cisternae
What is the ER lumen?
The space between ER membranes
What is the rough ER studded with?
Ribosomes
What does the rough ER produce?
Glycoproteins, phospholipids, and other proteins
What does the rough ER do?
Separates and transports proteins out by transport vesicles
The smooth ER lacks?
Ribosomes
What does the smooth ER produce?
Lipids
What does the smooth ER do?
- Detoxyfies the cell - adds hydroxyl groups to drugs
- Storage of calcium ions -triggers muscle contractions
- Metabolises carbs
What is the Golgi Apparatus?
A series of flattened sacs called cisternae
What side of the golgi does the Cis side face?
The rough ER (the receiving end)
What side of the golgi does the trans side face?
Points out towards the rest of the cell (shipping end)
Vesicles bring material from the (blank) to the (blank), fusing with the Golgi membrane
(rough ER), (Cis face)
Vesicles pinch off of the (blank) and head to their final destination within or outside of the cell
Trans face
What is the lysosome made up of?
Membranous sac of hydrolytic enzymes
What does the lysosome do?
Breaks down macromolecules into monomers
Why aren’t the contents of a lysosome digested if it ruptures?
Because the cytosol pH is too high for the enzymes
What are the types of intracellular digestion?
Phagocytosis
Autophagy